Inducers vs. inhibitors

Question 1

Inhibitors?

Answer 1

AO DEVICES - allopurinol, omeprazole, disulfiram, erythromycin (+ clarithromycin), valproate, isoniazid, ciprofloxacin, ethanol (acute), sulphonamides

• ketoconazole, fluconazole, metronidazole
• grapefruit juice
• cimetidine

Question 2

Inducers?

Answer 2

PCBRAs:

• phenytoin
• carbamezepine
• barbiturates (phenobarbital)
• rifampicin
• alcohol (chronic)
• sulphonylureas, st. johns wart + smoking
• Griseofulvin