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Pharm II Exam 3 > Indications > Flashcards

Indications Flashcards

1
Q

Treatment for premature ejaculation

A

Local anesthetics

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2
Q

Drugs that enhance libido

A

testostesterone

dopamine agonists

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3
Q

Prostaglandin E1 (alprostadil)

A

ED

Most commonly used pre-Viagra; efficacy up to 65%

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4
Q

Sildenafil

Viagra

A

ED- works on erection NOT on libido

Also used for BPH and pulmonary arterial HTN (PAH)

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5
Q

Calcium Gluconate (IV)

A

Calcium deficiency

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6
Q

Calcium Chloride (IV)

A

Calcium deficiency

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7
Q

Calcium Carbonate (po)

A

Calcium deficiency

Need to have H+ ion to free Ca2+ so must ingest with food bc stomach secretes H+ ion

Proton inhibitors will ↓ efficacy

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8
Q

Calcium Citrate-Malate (po)

A

Calcium deficiency

Good if pt taking proton inhibitors

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9
Q

Vitamin D

A

Vit D deficiency

Osteoporosis

Hypoparathyroidism

Rickets

Osteomalacia

2° Hyperparathyroidism

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10
Q

Calcitriol

1,25 -OH D3

A

Active form and most effective

Preferred agent fir vit D therapy

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11
Q

Teriparatide

hPTH 1-34

A

Severe osteoporosis

Only for pts at high risk of fx

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12
Q

Calcimimetic

A

Hyperparathyroidism

Hypercalcemia associated with parathyroid carcinoma

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13
Q

Raloxifen

A

Prevention and treatment of osteoporosis

Prophylaxis of invasive breast cancer

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14
Q

Biphosphonates

A

First line for osteoporosis prevention and tx

Must have adequate renal fn for IV use

Paget’s disease

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15
Q

Zoledronate

IV

A

Osteoporosis

Osteolytic lesions of multiple myeloma & breast ca

Hypercalcemia associated with malignancy

Pagets

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16
Q

Ibandronate

oral or IV

A

Last choice of biphosphonates for osteoporosis due to lack of date of hip fx reduction

Also not good for pagets

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17
Q

Denosumab

A

Osteoporosis prevention and tx

Bone met from solid tumors

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18
Q

Salmon Calcitonin

A

Last line therapy for Osteoporosis

Hypercalcemia

Paget’s disease

Intra-nasally administered

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19
Q

hPTH 1-84

not in US

A

Hypoparathyroidism

20
Q

Cortisol/Glucocorticoids

A

Immunosuppressant for:

Organ transplant (kidney)

Autoimmune disease

21
Q

Azathioprine

A

Immunosuppressant for:

Organ transplant
(kidney)

Autoimmune disease

22
Q

Mycophenolate Mofetil

A

Immunosuppressant for:

Organ transplant
(kidney)

Autoimmune disease

RA, myasthenia gravis, psoriasis, IBD

23
Q

Cyclosporine

A

Immunosuppressant for:

Organ transplant
(e.g. kidney)

Autoimmune disease-RA, IBD, psoriasis (off-label)

24
Q

Tacrolimus

A

Immunosuppressant for organ transplantation (e.g. kidney)

Preferred over cyclopsorine

25
Sirolimus | rapamycin
Immunosuppressant for organ transplantation (e.g. kidney)
26
Abatacept
Immunosuppressant Used for RA in patients unresponsive to TNF- alpha inhibitors
27
Adalimumab | Humira
Immunosuppressant RA Ulcerative colitis Crohn’s disease
28
Etanercept | Enbrel
Immunosuppressant Useful for many rheumatic syndromes (RA, AS, psoriasis); thought to be less effective against IBD’s compared to other TNF- alpha inhibitors
29
Infliximab | Remicade
Immunosuppressant RA Ulcerative colitis Crohn’s disease
30
Rituximab
Immunosuppressant Used for RA in patients unresponsive to TNF- alpha inhibitors Non-Hodgkin's lymphoma and chronic lymphocytic leukemia
31
Tocilizumab
Immunosuppressant Used for RA in patients unresponsive to TNF- alpha inhibitors
32
Cyclophosphamide
Lymphomas Leukemias MM Breast and ovarian ca Small cell lung cancer Some autoimmune conditions
33
Cisplatin
Testicular/Ovarian ca Bladder ca Small and non-small cell lung ca Colon ca
34
Streptozocin
Insulin-secreting islets carcinoma cells
35
Carmustine (bi-fn) Lomustine and Semustine (mono-fn)
Brain tumors
36
Methotrexate
Breast ca Head & Neck ca Bladder ca Lung carcinomas Lymphomas ALL
37
5-Fluorouracil
Colon ca Breast ca Gastroesophageal ca Hepatocellular ca Pancreatic carcinomas
38
6-Mercaptopurine
ALL and AML Crohn's
39
Vinblastine
Breast cancer Hodgkin’s and non-Hodgkin’s lymphoma
40
Vincristine
Childhood | leukemias and cancers
41
Paclitaxel
Ovarian, breast, bladder,ca Non-small cell lung cancers
42
Etoposide
Testicular ca Non-small cell and small cell lung ca AML and ALL Hodgkin’s and non-Hodgkin’s lymphoma
43
Irinotecan
Metastatic | colon cancer
44
Doxorubicin
Hodgkin’s and non-Hodgkin’s Breast, ovarian and bladder ca ALL NOT good for solid tumors
45
Bleomycin
Testicular carcinoma SCC Hodgkin’s and non-Hodgkin’s lymphomas
46
Allopurinol
Prevent hyperuricemia during 6-MP tx of leukemias

Pharm II Exam 3 (7 decks)

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