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Pharm II Exam 3 > Indications > Flashcards

Indications Flashcards

1
Q

Treatment for premature ejaculation

A

Local anesthetics

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2
Q

Drugs that enhance libido

A

testostesterone

dopamine agonists

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3
Q

Prostaglandin E1 (alprostadil)

A

ED

Most commonly used pre-Viagra; efficacy up to 65%

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4
Q

Sildenafil

Viagra

A

ED- works on erection NOT on libido

Also used for BPH and pulmonary arterial HTN (PAH)

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5
Q

Calcium Gluconate (IV)

A

Calcium deficiency

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6
Q

Calcium Chloride (IV)

A

Calcium deficiency

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7
Q

Calcium Carbonate (po)

A

Calcium deficiency

Need to have H+ ion to free Ca2+ so must ingest with food bc stomach secretes H+ ion

Proton inhibitors will ↓ efficacy

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8
Q

Calcium Citrate-Malate (po)

A

Calcium deficiency

Good if pt taking proton inhibitors

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9
Q

Vitamin D

A

Vit D deficiency

Osteoporosis

Hypoparathyroidism

Rickets

Osteomalacia

2° Hyperparathyroidism

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10
Q

Calcitriol

1,25 -OH D3

A

Active form and most effective

Preferred agent fir vit D therapy

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11
Q

Teriparatide

hPTH 1-34

A

Severe osteoporosis

Only for pts at high risk of fx

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12
Q

Calcimimetic

A

Hyperparathyroidism

Hypercalcemia associated with parathyroid carcinoma

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13
Q

Raloxifen

A

Prevention and treatment of osteoporosis

Prophylaxis of invasive breast cancer

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14
Q

Biphosphonates

A

First line for osteoporosis prevention and tx

Must have adequate renal fn for IV use

Paget’s disease

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15
Q

Zoledronate

IV

A

Osteoporosis

Osteolytic lesions of multiple myeloma & breast ca

Hypercalcemia associated with malignancy

Pagets

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16
Q

Ibandronate

oral or IV

A

Last choice of biphosphonates for osteoporosis due to lack of date of hip fx reduction

Also not good for pagets

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17
Q

Denosumab

A

Osteoporosis prevention and tx

Bone met from solid tumors

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18
Q

Salmon Calcitonin

A

Last line therapy for Osteoporosis

Hypercalcemia

Paget’s disease

Intra-nasally administered

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19
Q

hPTH 1-84

not in US

A

Hypoparathyroidism

20
Q

Cortisol/Glucocorticoids

A

Immunosuppressant for:

Organ transplant (kidney)

Autoimmune disease

21
Q

Azathioprine

A

Immunosuppressant for:

Organ transplant
(kidney)

Autoimmune disease

22
Q

Mycophenolate Mofetil

A

Immunosuppressant for:

Organ transplant
(kidney)

Autoimmune disease

RA, myasthenia gravis, psoriasis, IBD

23
Q

Cyclosporine

A

Immunosuppressant for:

Organ transplant
(e.g. kidney)

Autoimmune disease-RA, IBD, psoriasis (off-label)

24
Q

Tacrolimus

A

Immunosuppressant for organ transplantation (e.g. kidney)

Preferred over cyclopsorine

25
Q

Sirolimus

rapamycin

A

Immunosuppressant for organ transplantation (e.g. kidney)

26
Q

Abatacept

A

Immunosuppressant

Used for RA in patients unresponsive to TNF- alpha inhibitors

27
Q

Adalimumab

Humira

A

Immunosuppressant

RA

Ulcerative colitis

Crohn’s disease

28
Q

Etanercept

Enbrel

A

Immunosuppressant

Useful for many rheumatic syndromes (RA, AS, psoriasis); thought to be less effective against IBD’s compared to other TNF- alpha inhibitors

29
Q

Infliximab

Remicade

A

Immunosuppressant

RA

Ulcerative colitis

Crohn’s disease

30
Q

Rituximab

A

Immunosuppressant

Used for RA in patients unresponsive to TNF- alpha inhibitors

Non-Hodgkin’s lymphoma and chronic lymphocytic leukemia

31
Q

Tocilizumab

A

Immunosuppressant

Used for RA in patients unresponsive to TNF- alpha inhibitors

32
Q

Cyclophosphamide

A

Lymphomas

Leukemias

MM

Breast and ovarian ca

Small cell lung cancer

Some autoimmune conditions

33
Q

Cisplatin

A

Testicular/Ovarian ca

Bladder ca

Small and non-small cell lung ca

Colon ca

34
Q

Streptozocin

A

Insulin-secreting islets carcinoma cells

35
Q

Carmustine (bi-fn)

Lomustine and Semustine (mono-fn)

A

Brain tumors

36
Q

Methotrexate

A

Breast ca

Head & Neck ca

Bladder ca

Lung
carcinomas

Lymphomas

ALL

37
Q

5-Fluorouracil

A

Colon ca

Breast ca

Gastroesophageal ca

Hepatocellular ca

Pancreatic
carcinomas

38
Q

6-Mercaptopurine

A

ALL and AML

Crohn’s

39
Q

Vinblastine

A

Breast
cancer

Hodgkin’s and
non-Hodgkin’s lymphoma

40
Q

Vincristine

A

Childhood

leukemias and cancers

41
Q

Paclitaxel

A

Ovarian, breast, bladder,ca

Non-small cell lung
cancers

42
Q

Etoposide

A

Testicular ca

Non-small
cell and small cell
lung ca

AML and ALL

Hodgkin’s and non-Hodgkin’s
lymphoma

43
Q

Irinotecan

A

Metastatic

colon cancer

44
Q

Doxorubicin

A

Hodgkin’s
and non-Hodgkin’s

Breast, ovarian and
bladder ca

ALL

NOT good for solid tumors

45
Q

Bleomycin

A

Testicular carcinoma

SCC

Hodgkin’s and non-Hodgkin’s
lymphomas

46
Q

Allopurinol

A

Prevent hyperuricemia during 6-MP tx of leukemias

Pharm II Exam 3 (7 decks)

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