Indications Flashcards
Beta blockers
Arrhythmias, angina, HF, anxiety
Beta blockers arrhythmias
Rate control
Beta blockers angina
Decreases work of heart
Beta blockers HF
(Carvediol) reduces work of heart
Beta blockers anxiety
Hypertension - reduced BP only if SNS is overactive, but aren’t used for hypertension now
Alpha 1 blockers
Mild-moderate hypertension, benign prostatic hypertrophy
Alpha 1 blockers mild-moderate hypertension
Not suitable as mono therapy, decreases TPR thus MABP
Alpha 2 agonist
Hypertension (reduces BP), migraine, menopausal flushing
ACE inhibitors
Hypertension, congestive HF
ACE inhibitors hypertension
Arterial & venous dilation reducing BP
ACE inhibitors congestive HF
Reduces afterload & preload, reduces symp activity & cardiac remodeling caused by ANG2 (useful post MI) also useful in renal disease
Angiotensin receptor blocker
Use in hypertension & CHF when ACE inhibitors intolerable. Reduced bradykinin (vasodilator) accumulation or cough/angiodema
Statins
Most effective treatment for dyslipidaemia. 2* prevention of CVS disease, decrease mortality in those with pre-existing CVS disease
Most effective treat,ent for dyslipidaemia
Statins
Fibrates
Hypercholesterolemia usually combined with statins
Low dose aspirin
Prevention of thrombotic disease (post MI, AF), post CABG surgery, angina, mild-moderate pain
Clopidogrel
Prevention of thrombotic disease when aspirin is intolerable
Enoaxparin
Prevention of thrombotic disease, prevent/treat DVT, unstable angina, acute STEMI
Warfarin
Prevention of thrombotic disease (use in patients with MI, AF, prosthetic heart valve)
Fibrinolytics
Treatment of thrombotic disease (acute MI, PE, ischemic stroke), occlusion of central venous devices
Amlodipine
Hypertension, no bronchoconstriction or affect lipid profiles like beta blockers
Verapamil
Angina, hypertension
Verapamil angina
Reduces myocardial O2 demand & reduces coronary vasospasm
Diltiazem
Arrhythmias, angina
Diltiazem arrhythmias
Rate control
Diltiazem angina
Reduces myocardial O2 demand & reverses coronary vasospasm
Nitrates & nitrodilators
Acute angina & MI, long terms prophylaxis & management of coronary artery disease, HF, acute hypertensive emergency
Nitrates and nitrodilators acute angina and MI
GTN, symptomatic relief
Nitrates and nitrodilators long term prophylaxis/management of coronary artery disease
Isosprbide
Nitrates and nitrodilators acute hypertensive emergency
Sodium nitroprusside
Osmotic diuretic
Emergency reduction of intracranial pressure
Osmotic diuretic Emergency reduction of intracranial pressure
Acutely reduces cerebral intravascular volume
Loop diuretic
Hypertension, oedema, acute pulmonary oedema, hyperkalaemia, hypercalcemia
Loop diuretic hypertension
In decreased renal function
Thiazide diuretics
Hypertension, acute pulmonary hypertension
Thiazide diuretic acute pulmonary hypertension
Can be used in renal decrease if GFR is maintained
Thiazide diuretic hypertension
with ACEI/ARB & CCB
Potassium sparing diuretics
Hypertension, hyperaldosteronism, oedema with CHF & chronic liver failure, hyperkalaemia
Potassium sparing diuretics hyperkalaemia
With thiazide and frusemide
Potassium sparing diuretics hypertension
With ACEI/ARB
Sodium channel antagonist
Arrhythmias
Sodium channel antagonist arrhythmias
Polymorphic VT
Potassium channel antagonist
Arrhythmias
Potassium channel antagonist arrhythmias
Supraventricular and ventricular
Potassium channel antagonist interactions
Interacts with warfarin, digoxin and additive AV effect with BB
Cardiac glycoside
Arrhythmias
Cardiac glycoside arrhythmias
Rate control in HF