incubations

Question 1

leptospirosis

Answer 1

1-2weeks

Question 2

NTM

Answer 2

1-3 weeks

Question 3

parvovirus

• incubation
• when infectious
• rash duration

Answer 3

4-28 days
infectious in days PRECEDING rash/arthropathy
rasion 7-10 days

Question 4

HHV6

Answer 4

7-10 days

Question 5

rubella

• incubation
• infectious duration
• rash duration

Answer 5

• Incubation = 14-21 days
• Infectious period = 10 days after infection to up to 2 weeks post rash. Less infectious than measles
• rash 3 days

Question 6

measles

• incubation
• infectious period
• timing of rash

Answer 6

• Incubation = 10-14 days
• Infectious period = 3 days prior to 4 days after the rash
• rash within 3 days of the 3 c’s

Question 7

mumps

• incubation
• infectious period

Answer 7

• Incubation = 15-25 days
• 2 days before onset of illness > 4 days after
• 6 days prior to parotid swelling > 9 days post

Question 8

varicella

• incubation
• infectious period

Answer 8

• Incubation period = 10-21 days

- Infectious period = 1-2 days before rash until rash crusts. from 8-21 days post exposure

Question 9

EBV

• incubation
• infective period

Answer 9

• Incubation = 30-50 days

- Infective duration = > 6 months after acute infection then intermittently for life

Question 10

rhinovirus:

infectious period

Answer 10

Virus can be shed for up to 3 weeks after infection

Question 11

influenza

• incubation
• infectious period

Answer 11

• incubation = 2 days

- infectious: 24 hours prior to onset of symptoms for 4–7 days of illness.

Question 12

oseltamivir should be given when?

Answer 12

within 48h of symptom onset

Question 13

paraflu

• incubation
• infectious duration

Answer 13

• Incubation = 2-6 days

- Infectious duration = 2-3 weeks

Question 14

rotavirus incubation

Answer 14

1-3 days

Question 15

dengue incubation

Answer 15

1-7 days

Question 16

what is the vaccination strategy used against pertussis?

Answer 16

cocooning: immunisation of household contacts and carers of newborn infants

Question 17

pertussis vax schedule

Answer 17

3 dose primary schedule = 2, 4, 6 months
childhood boosters = 18mo, 4yo (effectiveness wanes to 50% by 5yo)
adolescents = x1 booster 
adulting = once every 10 years 
pregnancy = 3rd trim

Question 18

HPV vaccine made of what?

Answer 18

Recombinant virus-like particles (VLPs) = composed of L1 protein (outer virus layer) mimicking outer structure of HPV virion

Question 19

why is the menB vaccine so difficult to make?

Answer 19

MenB polysaccharide capsule similar to fetal nerve cells and therefore poorly immunogenic

Question 20

which vax are absolutely CI in egg allergy

Answer 20

Yellow fever and Q fever - contain higher amounts of ovalbumin

Question 21

when can you give live vax with steroid therapy

Answer 21

low dose <13days, or >4 weeks after treatment ceased

Question 22

how long after prbc or ivig can you give live vax

Answer 22

• 5 months after PRBC

* 9-11months after IVIG

Question 23

clostridium tetani

Answer 23

2-21 days

Question 24

pertussis

- incubation and infectious period

Answer 24

• incubation normally 7-10 days

- infectious just prior to and for 21 days after the onset of the cough if untreated

Question 25

N.meningitidis incubation and infectious period

Answer 25

both up to 10 days

Question 26

non-typhoid salmonella

Answer 26

Incubation period of 6-72 hours

Question 27

campylobacter

Answer 27

1 to 7 days incubation period