Increment 3

Question 1

Hazards can be classified as what 3 categories:

Answer 1

1. Hazard
2. Chemical
3. Biological

Question 2

What is the total quantity of a toxic agent administered?

Answer 2

Dose

Question 3

What is the concentration, frequency and duration to which personnel are subjected to a hazard?

Answer 3

Exposure

Question 4

What is the level of exposure at which an effect is first seen?

Answer 4

Threshold

Question 5

When do you see clinical signs of a toxic exposure?

Answer 5

Toxin exceeds threshold level

Question 6

What can affect the onset of clinical signs?

Answer 6

• Strength of the host and their individual defenses

- Acquired conditions/genetics can increase susceptibility to a toxin

Question 7

What is used to compare the relative toxicities of chemicals?

Answer 7

Quantitative Measure

Question 8

What kind of graph shows the progression of increasing doses?

Answer 8

Dose-response curve

Question 9

What is the study of how a substance gets into the body and what happens to that substance?

Answer 9

Toxicokinetics

Question 10

4 processes of toxicokinetics

Answer 10

1. Absorption
2. Distribution
3. Metabolism
4. Excretion