important rate limiting enzymes Flashcards

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1
Q

rate limitng step of the pentose phosphate pathway

A

glucose-6-phosphate dehydrogenase

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2
Q

which tissues of body use pentose phosphate pathway

(NADPH produces is used for?)

A

RBCs

Liver

adrenal cortex

mamary glands (during lactation)

its used in cholesterol and FA synthesis

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3
Q

why can a def in the rate limiting enzyme of HMp shunt (pentose phosphate pathway)

result in hemolytic anemia

A

bc G6PD

which makes NADPH which is used to make glutathinone (antioxidant)

thus no glutathione -> ROS damage to RBC

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4
Q

what is the rate limiting enzyme for?

Fatty acid SYNTHESIS

A

Acetyl-CoA carboxylase

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5
Q

what is the rate limiting enzyme?

B-oxidation of Fatty acids

A

Carnitine acyltransferase 1

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6
Q

what is the rate limiting enzyme?

Ketone body synthesis

A

HMG-CoA synthase

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7
Q

what is the rate limiting enzyme?

Cholesterol syntehsis

A

.HMG-CoA REDUCTASE

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8
Q
A
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