important rate limiting enzymes

Question 1

rate limitng step of the pentose phosphate pathway

Answer 1

glucose-6-phosphate dehydrogenase

Question 2

which tissues of body use pentose phosphate pathway

(NADPH produces is used for?)

Answer 2

RBCs

Liver

adrenal cortex

mamary glands (during lactation)

its used in cholesterol and FA synthesis

Question 3

why can a def in the rate limiting enzyme of HMp shunt (pentose phosphate pathway)

result in hemolytic anemia

Answer 3

bc G6PD

which makes NADPH which is used to make glutathinone (antioxidant)

thus no glutathione -> ROS damage to RBC

Question 4

what is the rate limiting enzyme for?

Fatty acid SYNTHESIS

Answer 4

Acetyl-CoA carboxylase

Question 5

what is the rate limiting enzyme?

B-oxidation of Fatty acids

Answer 5

Carnitine acyltransferase 1

Question 6

what is the rate limiting enzyme?

Ketone body synthesis

Answer 6

HMG-CoA synthase

Question 7

what is the rate limiting enzyme?

Cholesterol syntehsis

Answer 7

.HMG-CoA REDUCTASE