Imp Flashcards
Acetylcholine from cholinergic neurons have what actions? (5)
- Contraction of smooth muscle in wall
- relaxation of sphincters
- increase salivary secretion
- increase gastric secretion
- increase pancreatic secretion
Norepinephrine from adrenergic neurons have what actions? (3)
- Relaxation of smooth muscle in wall
- Contraction of sphincters
- increase in salivary secretion
Vasoactive intestinal peptide (VIP) from neurons of the ENS have what actions? (3)
- Relaxation of smooth muscle
- increase intestinal secretion
- increase pancreatic secretion
Nitric Oxide (NO) from neurons of the ENS has what action?
- Relaxation of smooth muscle
Gastrin-releasing peptide (GRP) from vagal neurons of the gastric mucosa has what action?
Increase in gastrin secretion
Enkepahlins from neurons of the ENS has what actions? (2)
- Contraction of smooth muscle
- decrease in intestinal secretion
Neurpeptide Y from neurons of the ENS has what actions (2)?
relaxation of smooth muscle
decrease intestinal secretion
Substance P which is co-secreted with ACh by neurons of the ENS have what actions?
- contraction of smooth muscle
- increase in salivary secretion
Our stomach is too acidic. What can we release to help respond to the low pH (acidic) environment?
Somatostatin from D cells in the GI mucosa, hypothalamus or the g cells of the pancrease will decrease H+ gastric secretions and decrease release of gastric hormones
After eat, what is realeased
gastrin
When we have a acidic (high amount of H+) or FA in the duodenum, what is released?
Secretin is released from S cells in the duodeum.
It will: [increase HCO3- secretion from the pancreas and biliary tract], [decrease gastric H+ release], [decrease atrophy of the GI mucosa].
Gastrin
Gastrin is relased from G cells in the mucosa after we eat: vagal stimulation, distension or presecne of smal lpeptides.
Releases H+ and causes trophy of the stomach mucus
What targets parietal cells to release HCl?
Histamine from ECL in the gastric pits
We just ate a meal and it moved into the SI. What happens if we sense FA or small peptides in the duodenum and jejunum
Release of CCK –> release of pancreatic secretions and HCO3- from the pancreas, bile from the GB, atropy of the GB and pancreas, slow of gastric emptying
What decreaes gastric H secretions and secretes insulin from pancreatic B cells
GIP