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Pharmacology Exam III > Immunosuppressants > Flashcards

Immunosuppressants Flashcards

0
Q

Dexamethasone

A

Decadron

Glucocorticoid

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1
Q

Cortisol

A

Hydrocortisone , Solu-Cortef

Half life 1-2 hours

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2
Q

Prednisolone

A

Glucocorticoid

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3
Q

Prednisone

A

Glucocorticoid

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4
Q

Methylprednisolone

A

Medrol

Glucocorticoid

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5
Q

Cyclosporin

A

Sandimmune
Calcineurin inhibitor
Break through drug allowing transplants
Nephro, hepato, cardio toxicity

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6
Q

Tacrolimus

A

Prograf
MUCH more potent than cyclosporin
More efficacious
More nephrotoxic, less cardiotoxic

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7
Q

Sirolimus

A

Rapamune
mTOR inhibitor
Nephrotoxicity, delayed wound healing
Only given oral

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8
Q

Azathioprine

A

Imuran
Anti Proliferative
Better for acute than chronic
Numerous side effects, bone marrow supression

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9
Q

Mycophenolate mofetil

A

Cellcept
Anti Proliferative
Side effects limited to GI and BM

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10
Q

Mycophenolate sodium

A

Myfortic
Anti proliferative
Designed to be slow releasing and less harmful
No evidence for this

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11
Q

Anti thymocyte ab

A

Monoclonal ab

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12
Q

Muromonab CD3

A

Othoclone OKT3

Anti lymphocyte ab

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Pharmacology Exam III (5 decks)

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