Immunophenotypes Flashcards
1
Q
CML
A
t(9;22)
2
Q
AML
A
t(8;21) has favorable prognosis, inverse (16) or t(16;16) also has good prognosis
3
Q
APL
A
t(15;17)
4
Q
ALL
A
t(12;21) has good prognosis, t(9:22) has intermediate prognosis, t(4:11) has poor prognosis
5
Q
Follicular lymphoma
A
t(14;18) - translocation of heavy-chain Ig (14) and BCL-2 (18). BCL2 inhibits apoptosis
6
Q
Burrkitt lymphoma
A
t(8:14), translocation of c-myc gene and Ig heavy chain
7
Q
Mantle cell lymphoma
A
t(11;14)
8
Q
Extra nodal marginal zone B cell lymphoma
A
t(11:18)
9
Q
Hairy cell leukemia
A
BRAF mutation
10
Q
Diffuse large B cell lymphoma
A
BCL2 and BCL6
