Immunopathology Miscellaneous Deck

Question 1

Agents that have the capacity for both positive and negative actions.

Answer 1

Immunomodulator

Question 2

Agents that stimulate the immune response.

Answer 2

Immunestimulant

Question 3

Substances which have the ability to attenuate the immune response

Answer 3

Immunosuppressants.

Question 4

Colony-stimulating factors, Interleukins, Interferons, MDP, Potent Immunopharmacology

Answer 4

Biological Response Modifiers

Question 5

Agents that boost a failing immune system (IVIG)

Answer 5

Immunopotentiator

Question 6

Naturally Acquired Active Immunity

Answer 6

Infection

Question 7

Naturally Acquired Passive Immunity

Answer 7

Placental transfer of IgG

Question 8

Artificially Acquired Active Immunity

Answer 8

Vaccines

Question 9

Artificially Acquired Passive Immunity

Answer 9

Administration of immunoglobulins.

Question 10

IL-1 Function

Answer 10

Lymphocyte + GF Activation
Induction of Inflammation

Question 11

IL-2 Function

Answer 11

Lymphocyte + NK Activation

Question 12

IL-4

Answer 12

Promote B +T GF
Macrophage Activation
IgE Production
Bone marrow precursor proliferation

Question 13

IL-6

Answer 13

Lymphocyte Growth Factor
Augments Inflammation
Hematopoietic Growth Factor

Question 14

TNF-Alpha

Answer 14

Neutrophil, endothelial, lymph and liver cell activation —> Produce acute phase reactants.

Question 15

TNF-beta

Answer 15

Tumorcidal

Question 16

IFN-alpha

Answer 16

NK and macrophage activation
Upregulates MHC I

Question 17

IFN-gamma

Answer 17

Macrophage and NK activation
MHC1 upregulation

Question 18

Primary Immunodeficiency

Answer 18

Genetic (i.e SCID)

Question 19

Secondary Immunodeficiency

Answer 19

Acquired (i.e immunosuppressive therapy)

Question 20

ANC

Answer 20

WBC * % neutrophils.

Question 21

Left Shift

Answer 21

bands >5%

Question 22

Neutropenia

Answer 22

<1500 WBC/mm^3

Question 23

CD3

Answer 23

T lymphocytes

Question 24

CD4

Answer 24

Helper T cells

Question 25

CD8

Answer 25

Cytotoxic T cells

Question 26

CD20

Answer 26

B-cells

Question 27

CD25

Answer 27

Activated T-lymphocytes, B-lymphocytes, IL02R

Question 28

CD56

Answer 28

Natural Killer Cells

Question 29

Anergy

Answer 29

Lack of cell-mediated response.

Question 30

Basic Recall Antigens

Answer 30

Candida Albicans
Mumps
Trichophyton
Tuberculin

Question 31

Active Infection Immunoglobulin

Answer 31

IgM

Question 32

Memory Immunoglobulin

Answer 32

IgG

Question 33

Rheumatoid Arthritis Cytokine

Answer 33

TNF-alpha

Question 34

Most common type of monoclonal antibody

Answer 34

IgG

Question 35

Conjugated Monoclonal Antibodies

Answer 35

Attached to a toxin, or drug agent to enhance delivery to site of action.

Question 36

MoAB Targets

Answer 36

Surface Antigens
Growth Factor Receptors

Question 37

Immunological responses to environmental or endogenous antigens that can result in disease and be clinically harmful.

Answer 37

Allergens

Question 38

Disturbance in immunological tolerance with response to auto-antigens

Answer 38

Autoimmunity

Question 39

Immune system of host mounts an immunological response to tissue of another individual in host.

Answer 39

Alloimmunity.

Question 40

Type I/ Anaphylaxis Mediator

Answer 40

IgE

Question 41

Penicillin Allergy Skin Testing Major Determinant

Answer 41

Penicilloyl

Question 42

Highest Cross Reactivity with Cephalosporins

Answer 42

Aminopenicillins

Question 43

Safe to use with penicillins

Answer 43

Aztreonam

Question 44

ABO Mismatched Transfusion Reaction
Hemolytic Anemia
Erythroblastosis Fetalis

Answer 44

Type II Hypersensitivity

Question 45

Arthus Reaction
Serum Sickness
Drug Induced lupus

Answer 45

Type II Hypersensitivity

Question 46

Signs of Drug Induced Lupus

Answer 46

Elevated ANA
SS-DNA
ESR

Question 47

Contact Dermatitis
Tuberculin Skin Test

Answer 47

Type IVa hypersensitivity

Question 48

SJS
TEN

Answer 48

Type IVc hypersensitivity

Question 49

AGEP

Answer 49

Type IVd hypersensitivity