Immunology / Immune System Flashcards

1
Q

What is another name for antibody

A

Immunoglobulin

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2
Q

Which type of cell of the Immune system produces antibodies

A

B cell

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3
Q

What is the main role of antibodies

A

preventing a virus from producing itself quickly

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4
Q

What are the 5 antibody types

A

Immunoglobulin A (IgA), IgD, IgE, IgG, IgM

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5
Q

Which of the following best describes antibody - mediated immunity

a) branch of the immune system which combats antigens from pathogens that are freely circulating, or outside the infected cells
b) enabled by antigen production from B cells
c) also known as humoral immunity
d) all of the above

A

Answer: d) all of the above

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6
Q

Immunoglobulins are able to identify and block specific antigens

True or false

A

Answer: true

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7
Q

The complement system is an enzyme group in the blood which activated:

A

Various pathways in the innate immune system to fight infection

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8
Q

Which cell produces histamine

A

Mast cell

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9
Q

Which of the following is not part of cell-mediated immunity?

A) a type of immunity which involves antibodies
B) involves activation of phagocytes to destroy pathogens
C) triggering of cytokines enabling moderation of other parts of the immune system
D) a type of immunity which does not involve antibodies

A

A) a type of immunity which involves antibodies

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10
Q

Adaptive and specific immunity are the same

A

Yes they are

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11
Q

What is phagocytosis

A

It’s the process of macrophages and other phagocytes like neutrophils use in order to destroy pathogens

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12
Q

What leads to inflammation

A

When the infection is too hard to fight it releases signalling proteins called cytokines this leads to inflammation

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13
Q

What cells do cytokines activate in the innate immune system

A

Macrophages, monocytes and neutrophils

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14
Q

What other processes does the inflammatory response involve in that help to fight the infection

A

Vasodilation, increased vascular permeability, mast cell activation and degranulation, activation of clotting system, activation of kinin system

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15
Q

What is the acute phase response

A

inflammation stimulates neutrophils and macrophages to secrete more cytokines a chemical called interleukins, this is called acute inflammatory response which involves sending interleukins1 to the brain: fever, reduce appetite, tiredness and sends interleukins6 to liver, interleukins8, 2 and 12 and TNF is released

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16
Q

What are opsonins

A

They are Complex molecules that attach to pathogens, make it easier for macrophages and neutrophils to recognise and phagocytose that pathogen

17
Q

What is the specific immune system

A

It involves lymphocytes, T and B cells, they stay in the lymph nodes and the mucosa associated lymph node tissue

18
Q

What is lysozyme

A

Lysozyme splits the peptidoglycan of bacterial cell walls.

19
Q

Acute inflammation can be initiated by:

A

Activation of mast cells releases chemotactic factors for neutrophils and also vasoactive mediators such as histamine.

20
Q

A special feature of adaptive immunity is:

A

Ability to distinguish self and non self

21
Q

How are antibody producing cells stimulated?

A

Antibody producing B cells are activated via interactions with T helper cells

22
Q

Cytotoxic T cells can be activated via which of the following?

A

By identifying virus peptides presented by MHC-I

23
Q

What happens to the immune system in autoimmune disease ?

A

Antibodies from the immune system mistakenly attack the body’s tissues

24
Q

Lymph is circulated by
Question 1 Select one or more:

a. The beating of the heart and gravity

b. Gravity and skeletal muscle contraction

c. Changes in thoracic pressure

d. Contraction of adjacent muscles and the pulsation of large arteries

A

Contraction of adjacent muscles and the pulsation of large arteries, Changes in thoracic pressure

25
Lymphatic capillaries are Question 2 Select one: a. Equipped with valves b. Thick-walled c. In direct communication with blood capillaries d. Blind ended
Blind ended
26
Lymphatics contain lymph nodes located at certain intervals along their course Question 3 Select one: a. False b. True
True
27
Lymphatics have thinner walls than large veins Question 4 Select one: a. True b. False
True
28
Mucosa-associated lymphoid tissue are associated with the Question 5 Select one or more: a. Arm-pits b. Gastrointestinal tract c. Respiratory tract d. Spleen
Gastrointestinal tract, Respiratory tract
29
What happens in the lymph nodes as lymph flows through them Question 6 Select one or more: a. White blood cells are made b. Reticular fibres filter debris c. Plasma and mature T cells are added d. Foreign substances are destroyed
Reticular fibres filter debris, Plasma and mature T cells are added, Foreign substances are destroyed
30
Which best describes a lymph node Question 7 Select one: a. A type of pathogen that attacks the immune system b. Any organ that is being attacked by pathogens c. A special kind of immune cell that is found in the lymph d. A capsule in the lymph vessel that is filled with B cells and T cells
A capsule in the lymph vessel that is filled with B cells and T cells
31
Which of the following is NOT a function of the lymphatic system Question 8 Select one: a. Transporting interstitial fluid back to the bloodstream b. Providing immunological defences c. Filtering metabolic wastes d. Transporting absorbed fats from the intestine to the blood
Filtering metabolic wastes
32
Which of the following is NOT part of the lymphatic system Question 9 Select one: a. Bone marrow b. Thymus and spleen c. Liver d. Adenoids and tonsils
Liver
33