Immunology / Immune System Flashcards
What is another name for antibody
Immunoglobulin
Which type of cell of the Immune system produces antibodies
B cell
What is the main role of antibodies
preventing a virus from producing itself quickly
What are the 5 antibody types
Immunoglobulin A (IgA), IgD, IgE, IgG, IgM
Which of the following best describes antibody - mediated immunity
a) branch of the immune system which combats antigens from pathogens that are freely circulating, or outside the infected cells
b) enabled by antigen production from B cells
c) also known as humoral immunity
d) all of the above
Answer: d) all of the above
Immunoglobulins are able to identify and block specific antigens
True or false
Answer: true
The complement system is an enzyme group in the blood which activated:
Various pathways in the innate immune system to fight infection
Which cell produces histamine
Mast cell
Which of the following is not part of cell-mediated immunity?
A) a type of immunity which involves antibodies
B) involves activation of phagocytes to destroy pathogens
C) triggering of cytokines enabling moderation of other parts of the immune system
D) a type of immunity which does not involve antibodies
A) a type of immunity which involves antibodies
Adaptive and specific immunity are the same
Yes they are
What is phagocytosis
It’s the process of macrophages and other phagocytes like neutrophils use in order to destroy pathogens
What leads to inflammation
When the infection is too hard to fight it releases signalling proteins called cytokines this leads to inflammation
What cells do cytokines activate in the innate immune system
Macrophages, monocytes and neutrophils
What other processes does the inflammatory response involve in that help to fight the infection
Vasodilation, increased vascular permeability, mast cell activation and degranulation, activation of clotting system, activation of kinin system
What is the acute phase response
inflammation stimulates neutrophils and macrophages to secrete more cytokines a chemical called interleukins, this is called acute inflammatory response which involves sending interleukins1 to the brain: fever, reduce appetite, tiredness and sends interleukins6 to liver, interleukins8, 2 and 12 and TNF is released
What are opsonins
They are Complex molecules that attach to pathogens, make it easier for macrophages and neutrophils to recognise and phagocytose that pathogen
What is the specific immune system
It involves lymphocytes, T and B cells, they stay in the lymph nodes and the mucosa associated lymph node tissue
What is lysozyme
Lysozyme splits the peptidoglycan of bacterial cell walls.
Acute inflammation can be initiated by:
Activation of mast cells releases chemotactic factors for neutrophils and also vasoactive mediators such as histamine.
A special feature of adaptive immunity is:
Ability to distinguish self and non self
How are antibody producing cells stimulated?
Antibody producing B cells are activated via interactions with T helper cells
Cytotoxic T cells can be activated via which of the following?
By identifying virus peptides presented by MHC-I
What happens to the immune system in autoimmune disease ?
Antibodies from the immune system mistakenly attack the body’s tissues
Lymph is circulated by
Question 1 Select one or more:
a. The beating of the heart and gravity
b. Gravity and skeletal muscle contraction
c. Changes in thoracic pressure
d. Contraction of adjacent muscles and the pulsation of large arteries
Contraction of adjacent muscles and the pulsation of large arteries, Changes in thoracic pressure