Immunology: Hypersensitivity/allergy Flashcards

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1
Q

Anaphylatic Reaction/ anaphylaxic

A

Involves iGE antibodies which binds to basophils/Mast cells

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2
Q

1st Exposure

A

IgE (to the allergen) is formed and binds to Mast cells FC portion. (no symptom at this point)

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3
Q

2nd exposure

A

Degranulation of mass cells/basophils
Histamine, Leukotriene and Prostaglandins repleased

  1. dilates blood vessels
  2. increased permeability of capullary vessels
  3. contraction of smooth muscles
  4. increased mucus secretion
  5. increased secretion of HCl in stomach
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