Immunology (hard to remember)

Question 1

Kupffer Cells

Answer 1

Macrophage in the liver

Question 2

Alveolar Macrophage

Answer 2

Macrophage in the lungs

Question 3

Function of B cells

Answer 3

ANTIBODIES
Clean up of remaining viruses after a T-cell attack
Inactivate viruses for macrohpages to engulf and destroy

Question 4

Hypothalamus

Answer 4

Control centre

Question 5

Pituitary Gland

Answer 5

Major gland

Question 6

Gland that produces aldosterone and cortisol

Answer 6

Adrenal Gland - Cortex

Question 7

CRP

Answer 7

1) Diagnosis
2) Enchance Phagocytosis - tastey
3) Complement activation

Question 8

Histamine

Answer 8

neurotransmitter (cytokine)
mediator of pruitis 
increases vascular permeability
Vasodilation
Contraction of smooth muscle

Question 9

Stromal Cell

Answer 9

Connective tissue cell of any organ

Question 10

A molecule that enchances phagocytosis by marking an antigen for an immune response

Answer 10

Opsonin

Question 11

Opsonin examples

Answer 11

C3b
CRP
Antibodies

Question 12

Fc receptors

Answer 12

found on phagocytes

bind to constant regions of Ig(s)

Question 13

ADCC

Answer 13

Antibody Dependant Cell-mediated Cytotoxidity

Question 14

Antibody heavy chain switching (class switching)

Answer 14

B cells switch the antibody heavy chain constant region gene segment that they use

Question 15

Generation of hight affinity antibodies - somatic hypermutation

Answer 15

Aim -to produce antibodies that recognise the same antigen but with increased affinity
Point mutations made in the heavy / light chain gene segments that encode for the variable antigen binding sites of antibodies