Immunology and Disorders Flashcards
Scleritis is what type of hypersensitivity reaction?
III
OCP is what type of hypersensitivity reaction?
II
Which type of reaction that activates complement?
II
Which type of reaction occur when antigen-antibody complexes accumulate in tissue to attract leukocytes?
III
PUK is what type of reaction?
III
If Basophils or mast cells are seen on cytology what does it imply?
Vernal conjunctivitis
Contact dermatoblepharitis has what type of reactions?
- type I 2. Type IV
Vernal KC is what type of reaction?
I and IV
In VKC the (GIANT) papillary reaction occurs mostly where?
Upper palpebral conj
Thickened gelatinous mounds with vascular injection is called what and see in what
Horner Trantus dots (macroaggregates of degeneated eosinophils and epithelial cells), VKC
Shield ulcer occurs with what disease?
VKC - develop in the superior or central cornea.
How does AKC (atopic) differ from VKC?
- AKC have disease year-round. 2. AKC patients are older 3 AKC papillae are smaller and on both upper and lower 4. in AKC extensive Corneal vascularization and opacification secondary to chronic epithelial disease can occur.
Ligneous conjunctivitis has been linked to what systemic deficiency?
Type I plasminogen.
When does stromal keratitis from congenital syphillus develop?
Late in the first decade - or even later
What are 5 nonocular signs of congential syphillus?
- dental deformities 2. bone and cartilage abnl 3. CN VIII deafness 4. Rhagades (circumoral radiating scars) 5. MR
What are the characteristics of acquired syphilic stromal keratitis?
typically U/L; uveitis and retinitis are much more common manifestations of acquired syphilis than keratitis.
In Cogan Syndrome when does the URI occur?
1-2 weeks before the eye and ear symptoms.
PUK happens usually with what systemic dx?
RA (also seen in Wegners, SLE, Polyarteritis noduosa, ulcerative colitis,)
Which one is painful: PUK or Moorens?
Mooren’s
Which one has scleral and corneal involvement PUK or Moorens?
PUK
What kind of corneal movement does Mooren’s have?
Starts peripherally and spreads circumferentially and then centripetally with a leading undermined edge of de-epithelized tissue. A slower movement of ulceration proceeds toward the sclera.
What systemic disease is associated with Mooren ulcer type PUK?
Hepatitis C
Mooren’s dz is a/w with what systemic illness?
NONE.. by defintion it has no underlying systemic illness
Neomycin causes what to the cornea and what type of immune reaction?
Peripheral corneal infiltratres; Wessely immune ring; TYPE 3 rxn
