Immunology and Disorders Flashcards

1
Q

Scleritis is what type of hypersensitivity reaction?

A

III

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2
Q

OCP is what type of hypersensitivity reaction?

A

II

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3
Q

Which type of reaction that activates complement?

A

II

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4
Q

Which type of reaction occur when antigen-antibody complexes accumulate in tissue to attract leukocytes?

A

III

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5
Q

PUK is what type of reaction?

A

III

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6
Q

If Basophils or mast cells are seen on cytology what does it imply?

A

Vernal conjunctivitis

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7
Q

Contact dermatoblepharitis has what type of reactions?

A
  1. type I 2. Type IV
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8
Q

Vernal KC is what type of reaction?

A

I and IV

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9
Q

In VKC the (GIANT) papillary reaction occurs mostly where?

A

Upper palpebral conj

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10
Q

Thickened gelatinous mounds with vascular injection is called what and see in what

A

Horner Trantus dots (macroaggregates of degeneated eosinophils and epithelial cells), VKC

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11
Q

Shield ulcer occurs with what disease?

A

VKC - develop in the superior or central cornea.

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12
Q

How does AKC (atopic) differ from VKC?

A
  1. AKC have disease year-round. 2. AKC patients are older 3 AKC papillae are smaller and on both upper and lower 4. in AKC extensive Corneal vascularization and opacification secondary to chronic epithelial disease can occur.
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13
Q

Ligneous conjunctivitis has been linked to what systemic deficiency?

A

Type I plasminogen.

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14
Q

When does stromal keratitis from congenital syphillus develop?

A

Late in the first decade - or even later

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15
Q

What are 5 nonocular signs of congential syphillus?

A
  1. dental deformities 2. bone and cartilage abnl 3. CN VIII deafness 4. Rhagades (circumoral radiating scars) 5. MR
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16
Q

What are the characteristics of acquired syphilic stromal keratitis?

A

typically U/L; uveitis and retinitis are much more common manifestations of acquired syphilis than keratitis.

17
Q

In Cogan Syndrome when does the URI occur?

A

1-2 weeks before the eye and ear symptoms.

18
Q

PUK happens usually with what systemic dx?

A

RA (also seen in Wegners, SLE, Polyarteritis noduosa, ulcerative colitis,)

19
Q

Which one is painful: PUK or Moorens?

A

Mooren’s

20
Q

Which one has scleral and corneal involvement PUK or Moorens?

A

PUK

21
Q

What kind of corneal movement does Mooren’s have?

A

Starts peripherally and spreads circumferentially and then centripetally with a leading undermined edge of de-epithelized tissue. A slower movement of ulceration proceeds toward the sclera.

22
Q

What systemic disease is associated with Mooren ulcer type PUK?

A

Hepatitis C

23
Q

Mooren’s dz is a/w with what systemic illness?

A

NONE.. by defintion it has no underlying systemic illness

24
Q

Neomycin causes what to the cornea and what type of immune reaction?

A

Peripheral corneal infiltratres; Wessely immune ring; TYPE 3 rxn

25
Q

How do you treat Stevens Johnson Syndrome?

A
  1. Pulsed IV steriods

2. Amniotic membrane

26
Q

ANA is positive in which disorder most commonly?

A

SLE (RA is ANA -)

27
Q

What is the most common ocular finding of SJS?

A

Episcleritis

28
Q

What is the order of potency for topical prednisolone?

A

Pred acetate 1%> pred phosphate > loteprednol > FML