Immunology Flashcards
1
Q
- Cell signaling proteins
- Often released by immune cells
- Stimulate inflammatory response
A
Cytokines
2
Q
Macrophage receptor for endotoxin
A
CD14
3
Q
Immune cell receptor for peptidoglycan cell wall
A
NOD receptors
4
Q
Three key functions: • Phagocytosis
• Cytokine production
• Antigen presentation
A
Monocytes and Macrophages
5
Q
Stimulates acute phase protein production in liver
A
IL-6
6
Q
Promotes Th1 development (cell-mediated response)
A
IL-12
7
Q
Small granules of neutrophils
Can be released in extracellular space
A
Alkaline phosphatase, collagenase, lysozyme, lactoferrin
8
Q
Larger (azurophilic or primary)
A
Acid phosphatase, myeloperoxidase
Fuse with phagosomes only
9
Q
Cytotoxic enzymes of eosinophil
A
Majorbasic protein (MBP)
• Eosinophilic cationic protein(ECP)
• Eosinophil peroxidase (EPO)
• Eosinophil-derived neurotoxin (EDN)
