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ISBB > Immunology > Flashcards

Immunology Flashcards

1
Q

Heart and lung migration

A

ASH
Ascaris
Strongyloides
Hookworm

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2
Q

Chemotactic agents or chemoattractants (2)

A

C5a and C3a

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3
Q

Impaired chemotaxis of wbcs -

Impaired random movement and chemotaxis of wbcs -

A
  1. job syndrome

2. Lazy leukocyte syndrome

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4
Q

Laboratory evaluation of Wbc movement (2)

A

Boyden Chamber

Migration through Agarose Gel

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5
Q

Opsonins (4)

A

C3b
C4b
iC3b
C1q

(CRP, Fibronectin, Fc of IgG)

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6
Q

Lysosomal Enzymes (3)

A

Lactoferrin
Lysozyme
Defensins

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7
Q

Defect in lysosomal enzymes

A

Chediak Higashi Syndrome

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8
Q

Defect in REACTIVE OXYGEN INTERMEDIATES

A

Chronic Granulomatous Disease (associated with McLeod phenotype -Kell)

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9
Q

Screening Test for Chronic Granulomatous Disease

A

Nitroblue Tetrazolium Test (formazan formation) or Neutrophil Reduction Test

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10
Q

Beta Lysin is bactericidal for Gram + except

A

Streptococcus

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11
Q

Interleukin for T Cell growth factor

A

IL-2

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12
Q

Interleukin multi colony stimulating factor

A

IL 3

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13
Q

Interleukin that activates eosinophils

A

IL 5

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14
Q

Marker for mature T Cell

A

CD 3

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15
Q

Marker for activated T or B cell

A

CD 25

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16
Q

Oligoclonal activators

A

Superantigens

17
Q

Mitogens

A

Polyclonal activators

18
Q

Complement is found in what region during serum protein electrophoresis

A

Beta region

19
Q

Hereditary angioneurotic edema (HANE) deficiency in what complement protein

A

C1 INH

20
Q

Immune complex disorder - SLE -like Syndrome

A

C2 and C4

21
Q

Neisseria infections complement deficiency

A

C5-C8

22
Q

Severe recurrent infections, glomerulonephritis

A

C3

23
Q

HLA phenotyping Ag detection principle

A

Complement-dependent lymphocytotoxicity

24
Q

Secondary lymphoid tissue presents Ag in Small Intestine

A

Peyer’s patches

25
Q

AB cis genotype is

A

inheritance of 3 ABO genes AB/O

ISBB (3 decks)

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