immunology Flashcards
what activates neutrophils
PAMPS
pro inflammatory mediators such as tnf alpha
what three killing mechanisms do neutrophils have
phagocytosis
degranulation
nets
what can pathogens be coated in to enhance phagocytosis
opsonins
what substances do mast cells produce
histamine
leukotrienes
cytokines (eg tnf alpha)
what is the first antibody made in response to an infection
igm
what is the most abundant antibody
igg
what antibody can cross the placenta
igg
what is the least abundant antibody
igd
what antibody is found in secretory fluids
iga
what antibody is responsible for allergic reactions
ige
what do MHC class1 present antigens to
CD8+ cells
what do MHC class 2 present antigens to
CD4+ cells
what do CD4+ cells become
t helper cells
what do CD8+ cells become
cytotoxic t cells
