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RACP Clinical Exam > Immunology > Flashcards

Immunology Flashcards

1
Q

Dolutegravir mechanism of action and contraindications.

A

Integrate Inhibitor

Hepatotoxicity
Renal Impairment
First trimester pregnancy

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2
Q

Emtricitabine mechanism and contraindications/precautions.

A

NRTI

Hepatitis B flare following cessation
Renal impairment
Lactic acidosis

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3
Q

Entecavir MOA and precautions

A

Viral polymerase inhibitor

Lactic acidosis with hepatomegaly
Hep B flare on cessation
HIV resistance if used as single agent
Renal and hepatic toxicity

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4
Q

Abacavir moa and precautions

A

NRTI

Hypersensitivity HLA B5701
Cardiovascular disease
Hepatic injury

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5
Q

What HIV drugs can be used in CKD?

A

Abacavir
Emtricitabine
Lamivudine

There is no triple therapy combination that can be safely used in significant CKD

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RACP Clinical Exam (13 decks)

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