Haematology Flashcards

1
Q

What are the haematological indications for autologous transplant?

A

Multiple myeloma

Relapsed/refractory lymphoma

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2
Q

What are the haematological indications for allogenic transplant?

A
AML
ALL
MDS
Aplastic anaemia 
Relapsed/refractory lymphoma
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3
Q

What are the stages of AGVHD?

A
  1. Skin
  2. Gut
  3. Liver
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4
Q

What are the preventative therapies for AGVHD?

A

Cyclosporine

Methotrexate

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5
Q

What is the treatment of acute GVHD?

A

First line - Methylprednisone

Second line - ATG, infliximab, etanercept

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6
Q

What is the treatment of hepatic sinusoidal obstructive Syndrome post allogeneic stem cell transplant.

A

Defibrotide

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7
Q

What is the prevention for Hepatic venous sinusoidal obstruction?

A

Heparin subcut

Usodeoxycholic acid

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8
Q

What are the complications you ask about in a patient with Multiple Myeloma?

A
Medication induced 
Metabolic 
Malignancy 
Anaemia 
Hypercalcaemia 
Bone disease and fractures
Renal Disease 
Neuropathy 
Thromboembolism
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