Immunology Flashcards
1
Q
wt type of hypersensitivy rxn will cause granulomas?
A
Type IV
2
Q
wt cells do MHC class 1 activate? 2?
A
1 = CD8 2 = CD4
3
Q
immune mediator that activated macrophages?
wt releases it?
A
INF- gamma
Th1 release
4
Q
drug that inhibits calcineurin and thus T-cell activation via IL-2?
major AE?
3 things it txs?
A
Cyclosporine
Nephrotoxicity
transplant rejection
Rheumatoid arthritis
psoriasis
5
Q
wc Ig can be produced in absence of CD4 cells? how does this relate to HIV?
A
IgM
it is main Ig bc lack of CD4 cells
