Immunology Flashcards
1
Q
What is the immune system for?
A
To identify and eliminate microorganisms and other harmful substances
2
Q
What are the 4 main clinical features suggestive of immunodeficiency?
A
Serious infections
Persistent infections
Unusual infections
Recurrent infections
3
Q
What are the 2 classifications of immunodeficiencies? and which is common/rare?
A
Secondary (common)
Primary (Rare)
4
Q
What are some conditions associated with secondary immune deficiencies?
A
- Physiological immune deficiency
- Infection
- Treatment interventions
- Malignancy
- Biochemical and nutritional disorders
5
Q
Functions of phagocytes?
A
- Initiation and amplification of the inflammatory response
- Scavenging of cellular and infectious debris
- Ingest and kill microorganisms
- Produce inflammatory molecules which regulate other components of the immune system
- Resolution and repair
6
Q
What would happen if a patient’s phagocytes were unable to bind to endothelial adhesion molecules?
A
Recurrent bacterial and fungal infections, high neutrophil count in blood, deep tissue at site of infection with no pus formation
