immunology

Question 1

Innate immunity has evolved to recognize molecular patterns common to many classes of pathogens termed

Answer 1

PAMP

Question 2

Acts as sensors for extracellular infections

Answer 2

TLR

Question 3

transmembrane proteins that possess multiple carbohydrate recognition domains whose engagement with PAMP generates intracellular activation signal

Answer 3

c type lectin

Question 4

enzymatic protein belonging to the peptidase or protease families

Answer 4

cathepsin G

Question 5

An anti-microbial peptide secreted by human eccrine sweat glands onto the skin

Answer 5

dermicidin

Question 6

how does defensins function

Answer 6

they bind to microbial cell mem, and forms pore like membrane defects that allow efflux of essential ions and nutrients

Question 7

causes endothelium to become activated to produce ligands (selectin, integrin)

Answer 7

gamma IFN

Question 8

hallmarks of adaptive immunity

Answer 8

flexible and memory

Question 9

Responsive to bacterial infection; it is also the

secondary immune response

Answer 9

IgG

Question 10

Responsible for primary response

Answer 10

IgM

Question 11

Responsive to helminth-induced sickness; it becomes a marker for allergy if one has genetic propensity for allergies

Answer 11

IgE

Question 12

Responsible for mucosal immunity (GIT, Respiratory tract)

Answer 12

IgA

Question 13

Responsible for B cell activation and immunoglobulin switch

Answer 13

IgD