Immunology Flashcards
An X-linked immunodeficiency condition associated with a defect in CD40
- Bruton’s Aggammaglobulinemia
- Bare Lymphocyte Syndrome
- Leukocyte Adhesion Deficiency
- Hyper IgM Syndrome
- SCID
- Kostmann’s
- Cyclic Neutropenia
- Chronic Granulomatous disease
- Cytokines Deficiencies
Hyper IgM Syndrome
An immunodeficiency condition associated with a mutation in HAX1
- Bruton’s Aggammaglobulinemia
- Bare Lymphocyte Syndrome
- Leukocyte Adhesion Deficiency
- Hyper IgM Syndrome
- SCID
- Kostmann’s
- Cyclic Neutropenia
- Chronic Granulomatous disease
- Cytokines Deficiencies
Kostmann’s
A patient presents with current infections with mycobacteria, analysis shows a defect in IL12 receptor
- Bruton’s Aggammaglobulinemia
- Bare Lymphocyte Syndrome
- Leukocyte Adhesion Deficiency
- Hyper IgM Syndrome
- SCID
- Kostmann’s
- Cyclic Neutropenia
- Chronic Granulomatous disease
- Cytokines Deficiencies
Cytokines deficiency
An immunodeficiency which can be treated with IFN-y
- Bruton’s Aggammaglobulinemia
- Bare Lymphocyte Syndrome
- Leukocyte Adhesion Deficiency
- Hyper IgM Syndrome
- SCID
- Kostmann’s
- Cyclic Neutropenia
- Chronic Granulomatous disease
- Cytokines Deficiencies
Chronic Granulomatous Disease
An immunodeficiency characterised by high blood neutrophil levels and CD18 defect
- Bruton’s Aggammaglobulinemia
- Bare Lymphocyte Syndrome
- Leukocyte Adhesion Deficiency
- Hyper IgM Syndrome
- SCID
- Kostmann’s
- Cyclic Neutropenia
- Chronic Granulomatous disease
- Cytokines Deficiencies
Leukocyte adhesion deficiency
Gold standards investigation for diagnosing food allergy
- RAST
- Skin prick
- Dilutant
- Histamine
- IgE mediated mast cell degranulation
- Non-IgE mediated mast cell degranulation
- Food challenge
- Allergic rhinitis
- Acute angioedema
Food challenge
A young man present to GP in May complaining of stuffy nose and constant sneezing when playing tennis in Hyde Park
- RAST
- Skin prick
- Dilutant
- Histamine
- IgE mediated mast cell degranulation
- Non-IgE mediated mast cell degranulation
- Food challenge
- Allergic rhinitis
- Acute angioedema
Allergic rhinitis
A 50 year old man struggles breathing, gets a rash and feels dizzy after contrast KUB study
- RAST
- Skin prick
- Dilutant
- Histamine
- IgE mediated mast cell degranulation
- Non-IgE mediated mast cell degranulation
- Food challenge
- Allergic rhinitis
- Acute angioedema
Non-IgE mast cell degranulation
This is used as a positive control in a skin prick test
- RAST
- Skin prick
- Dilutant
- Histamine
- IgE mediated mast cell degranulation
- Non-IgE mediated mast cell degranulation
- Food challenge
- Allergic rhinitis
- Acute angioedema
Histamine
A patient with severe, extensive eczema requires an allergy investigation for suspected celery allergy
- RAST
- Skin prick
- Dilutant
- Histamine
- IgE mediated mast cell degranulation
- Non-IgE mediated mast cell degranulation
- Food challenge
- Allergic rhinitis
- Acute angioedema
RAST
Which antibody is characteristic of Autoimmune haemolytic anaemia?
- Anti-Glp-IIb
- C-ANCA
- Anti-RhD
- Intrinsic Factor
- Anti-acetylcholine receptor
- Thyroperoxidase
- Anti-TSH receptor
- Anti-CCP
- Anti-GBM
Anti-RhD
Which antibody is characteristic of autoimmune thrombocytopenia purpura?
- Anti-Glp-IIb
- C-ANCA
- Anti-RhD
- Intrinsic Factor
- Anti-acetylcholine receptor
- Thyroperoxidase
- Anti-TSH receptor
- Anti-CCP
- Anti-GBM
Anti-Glp-IIb
Which antibody is characteristic of myasthenia?
- Anti-Glp-IIb
- C-ANCA
- Anti-RhD
- Intrinsic Factor
- Anti-acetylcholine receptor
- Thyroperoxidase
- Anti-TSH receptor
- Anti-CCP
- Anti-GBM
Anti-acetylcholine receptor
Which antibody is characteristic of grave’s?
- Anti-Glp-IIb
- C-ANCA
- Anti-RhD
- Intrinsic Factor
- Anti-acetylcholine receptor
- Thyroperoxidase
- Anti-TSH receptor
- Anti-CCP
- Anti-GBM
Anti-TSH receptor
Which antibody is characteristic of wegeners?
- Anti-Glp-IIb
- C-ANCA
- Anti-RhD
- Intrinsic Factor
- Anti-acetylcholine receptor
- Thyroperoxidase
- Anti-TSH receptor
- Anti-CCP
- Anti-GBM
C-ANCA
Which drug is used in treatment of psoriasis, and acts on IL-12?
- Natalizumab
- Ustekinumab
- Basiliximab
- IFN-b
- Cyclophosphamide
- Mycophenolate
- Natalizumab
- Rituximab
- Denosumab
Ustekinumab
Which drug can cause progressive multimodal leukoencephalopathy?
- Natalizumab
- Ustekinumab
- Basiliximab
- IFN-b
- Cyclophosphamide
- Mycophenolate
- Natalizumab
- Rituximab
- Denosumab
Mycophenolate
Which drug, that works on anti-A integrin, can be used in severe MS?
- Natalizumab
- Ustekinumab
- Basiliximab
- IFN-b
- Cyclophosphamide
- Mycophenolate
- Natalizumab
- Rituximab
- Denosumab
Natalizumab
Which drug can be used in treatment of osteoporosis?
- Natalizumab
- Ustekinumab
- Basiliximab
- IFN-b
- Cyclophosphamide
- Mycophenolate
- Natalizumab
- Rituximab
- Denosumab
Denosumab
Which drug works on CD-20?
- Natalizumab
- Ustekinumab
- Basiliximab
- IFN-b
- Cyclophosphamide
- Mycophenolate
- Natalizumab
- Rituximab
- Denosumab
Rituximab
HIV virus uses this molecule for initial binding to a CD4 cell
- CXCR4
- CCR7
- GP-120
- GP-41
- Anti-p24-gag-IgG
- Mip-1a
- Th1
- Fox-p3
GP-120
HIV uses this molecule for confrontational change binding
- CXCR4
- CCR7
- GP-120
- GP-41
- Anti-p24-gag-IgG
- Mip-1a
- Th1
- Fox-p3
GP-41
This is a co-receptor for HIV attachment
- CXCR4
- CCR7
- GP-120
- GP-41
- Anti-p24-gag-IgG
- Mip-1a
- Th1
- Fox-p3
Cxcr4
This is a non-neutralising antibody against HIV
- CXCR4
- CCR7
- GP-120
- GP-41
- Anti-p24-gag-IgG
- Mip-1a
- Th1
- Fox-p3
Anti-p24-gag-IgG
This is a chemokine produced by CD8 cells fighting off HIV
- CXCR4
- CCR7
- GP-120
- GP-41
- Anti-p24-gag-IgG
- Mip-1a
- Th1
- Fox-p3
Mip-1a