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Ladies (+ Bradley) Path 2016 > Immunology > Flashcards

Immunology Flashcards

1
Q

An X-linked immunodeficiency condition associated with a defect in CD40

  1. Bruton’s Aggammaglobulinemia
  2. Bare Lymphocyte Syndrome
  3. Leukocyte Adhesion Deficiency
  4. Hyper IgM Syndrome
  5. SCID
  6. Kostmann’s
  7. Cyclic Neutropenia
  8. Chronic Granulomatous disease
  9. Cytokines Deficiencies
A

Hyper IgM Syndrome

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2
Q

An immunodeficiency condition associated with a mutation in HAX1

  1. Bruton’s Aggammaglobulinemia
  2. Bare Lymphocyte Syndrome
  3. Leukocyte Adhesion Deficiency
  4. Hyper IgM Syndrome
  5. SCID
  6. Kostmann’s
  7. Cyclic Neutropenia
  8. Chronic Granulomatous disease
  9. Cytokines Deficiencies
A

Kostmann’s

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3
Q

A patient presents with current infections with mycobacteria, analysis shows a defect in IL12 receptor

  1. Bruton’s Aggammaglobulinemia
  2. Bare Lymphocyte Syndrome
  3. Leukocyte Adhesion Deficiency
  4. Hyper IgM Syndrome
  5. SCID
  6. Kostmann’s
  7. Cyclic Neutropenia
  8. Chronic Granulomatous disease
  9. Cytokines Deficiencies
A

Cytokines deficiency

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4
Q

An immunodeficiency which can be treated with IFN-y

  1. Bruton’s Aggammaglobulinemia
  2. Bare Lymphocyte Syndrome
  3. Leukocyte Adhesion Deficiency
  4. Hyper IgM Syndrome
  5. SCID
  6. Kostmann’s
  7. Cyclic Neutropenia
  8. Chronic Granulomatous disease
  9. Cytokines Deficiencies
A

Chronic Granulomatous Disease

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5
Q

An immunodeficiency characterised by high blood neutrophil levels and CD18 defect

  1. Bruton’s Aggammaglobulinemia
  2. Bare Lymphocyte Syndrome
  3. Leukocyte Adhesion Deficiency
  4. Hyper IgM Syndrome
  5. SCID
  6. Kostmann’s
  7. Cyclic Neutropenia
  8. Chronic Granulomatous disease
  9. Cytokines Deficiencies
A

Leukocyte adhesion deficiency

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6
Q

Gold standards investigation for diagnosing food allergy

  1. RAST
  2. Skin prick
  3. Dilutant
  4. Histamine
  5. IgE mediated mast cell degranulation
  6. Non-IgE mediated mast cell degranulation
  7. Food challenge
  8. Allergic rhinitis
  9. Acute angioedema
A

Food challenge

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7
Q

A young man present to GP in May complaining of stuffy nose and constant sneezing when playing tennis in Hyde Park

  1. RAST
  2. Skin prick
  3. Dilutant
  4. Histamine
  5. IgE mediated mast cell degranulation
  6. Non-IgE mediated mast cell degranulation
  7. Food challenge
  8. Allergic rhinitis
  9. Acute angioedema
A

Allergic rhinitis

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8
Q

A 50 year old man struggles breathing, gets a rash and feels dizzy after contrast KUB study

  1. RAST
  2. Skin prick
  3. Dilutant
  4. Histamine
  5. IgE mediated mast cell degranulation
  6. Non-IgE mediated mast cell degranulation
  7. Food challenge
  8. Allergic rhinitis
  9. Acute angioedema
A

Non-IgE mast cell degranulation

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9
Q

This is used as a positive control in a skin prick test

  1. RAST
  2. Skin prick
  3. Dilutant
  4. Histamine
  5. IgE mediated mast cell degranulation
  6. Non-IgE mediated mast cell degranulation
  7. Food challenge
  8. Allergic rhinitis
  9. Acute angioedema
A

Histamine

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10
Q

A patient with severe, extensive eczema requires an allergy investigation for suspected celery allergy

  1. RAST
  2. Skin prick
  3. Dilutant
  4. Histamine
  5. IgE mediated mast cell degranulation
  6. Non-IgE mediated mast cell degranulation
  7. Food challenge
  8. Allergic rhinitis
  9. Acute angioedema
A

RAST

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11
Q

Which antibody is characteristic of Autoimmune haemolytic anaemia?

  1. Anti-Glp-IIb
  2. C-ANCA
  3. Anti-RhD
  4. Intrinsic Factor
  5. Anti-acetylcholine receptor
  6. Thyroperoxidase
  7. Anti-TSH receptor
  8. Anti-CCP
  9. Anti-GBM
A

Anti-RhD

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12
Q

Which antibody is characteristic of autoimmune thrombocytopenia purpura?

  1. Anti-Glp-IIb
  2. C-ANCA
  3. Anti-RhD
  4. Intrinsic Factor
  5. Anti-acetylcholine receptor
  6. Thyroperoxidase
  7. Anti-TSH receptor
  8. Anti-CCP
  9. Anti-GBM
A

Anti-Glp-IIb

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13
Q

Which antibody is characteristic of myasthenia?

  1. Anti-Glp-IIb
  2. C-ANCA
  3. Anti-RhD
  4. Intrinsic Factor
  5. Anti-acetylcholine receptor
  6. Thyroperoxidase
  7. Anti-TSH receptor
  8. Anti-CCP
  9. Anti-GBM
A

Anti-acetylcholine receptor

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14
Q

Which antibody is characteristic of grave’s?

  1. Anti-Glp-IIb
  2. C-ANCA
  3. Anti-RhD
  4. Intrinsic Factor
  5. Anti-acetylcholine receptor
  6. Thyroperoxidase
  7. Anti-TSH receptor
  8. Anti-CCP
  9. Anti-GBM
A

Anti-TSH receptor

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15
Q

Which antibody is characteristic of wegeners?

  1. Anti-Glp-IIb
  2. C-ANCA
  3. Anti-RhD
  4. Intrinsic Factor
  5. Anti-acetylcholine receptor
  6. Thyroperoxidase
  7. Anti-TSH receptor
  8. Anti-CCP
  9. Anti-GBM
A

C-ANCA

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16
Q

Which drug is used in treatment of psoriasis, and acts on IL-12?

  1. Natalizumab
  2. Ustekinumab
  3. Basiliximab
  4. IFN-b
  5. Cyclophosphamide
  6. Mycophenolate
  7. Natalizumab
  8. Rituximab
  9. Denosumab
A

Ustekinumab

17
Q

Which drug can cause progressive multimodal leukoencephalopathy?

  1. Natalizumab
  2. Ustekinumab
  3. Basiliximab
  4. IFN-b
  5. Cyclophosphamide
  6. Mycophenolate
  7. Natalizumab
  8. Rituximab
  9. Denosumab
A

Mycophenolate

18
Q

Which drug, that works on anti-A integrin, can be used in severe MS?

  1. Natalizumab
  2. Ustekinumab
  3. Basiliximab
  4. IFN-b
  5. Cyclophosphamide
  6. Mycophenolate
  7. Natalizumab
  8. Rituximab
  9. Denosumab
A

Natalizumab

19
Q

Which drug can be used in treatment of osteoporosis?

  1. Natalizumab
  2. Ustekinumab
  3. Basiliximab
  4. IFN-b
  5. Cyclophosphamide
  6. Mycophenolate
  7. Natalizumab
  8. Rituximab
  9. Denosumab
A

Denosumab

20
Q

Which drug works on CD-20?

  1. Natalizumab
  2. Ustekinumab
  3. Basiliximab
  4. IFN-b
  5. Cyclophosphamide
  6. Mycophenolate
  7. Natalizumab
  8. Rituximab
  9. Denosumab
A

Rituximab

21
Q

HIV virus uses this molecule for initial binding to a CD4 cell

  1. CXCR4
  2. CCR7
  3. GP-120
  4. GP-41
  5. Anti-p24-gag-IgG
  6. Mip-1a
  7. Th1
  8. Fox-p3
A

GP-120

22
Q

HIV uses this molecule for confrontational change binding

  1. CXCR4
  2. CCR7
  3. GP-120
  4. GP-41
  5. Anti-p24-gag-IgG
  6. Mip-1a
  7. Th1
  8. Fox-p3
A

GP-41

23
Q

This is a co-receptor for HIV attachment

  1. CXCR4
  2. CCR7
  3. GP-120
  4. GP-41
  5. Anti-p24-gag-IgG
  6. Mip-1a
  7. Th1
  8. Fox-p3
A

Cxcr4

24
Q

This is a non-neutralising antibody against HIV

  1. CXCR4
  2. CCR7
  3. GP-120
  4. GP-41
  5. Anti-p24-gag-IgG
  6. Mip-1a
  7. Th1
  8. Fox-p3
A

Anti-p24-gag-IgG

25
Q

This is a chemokine produced by CD8 cells fighting off HIV

  1. CXCR4
  2. CCR7
  3. GP-120
  4. GP-41
  5. Anti-p24-gag-IgG
  6. Mip-1a
  7. Th1
  8. Fox-p3
A

Mip-1a

Ladies (+ Bradley) Path 2016 (5 decks)

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