immunology

Question 1

What is Type I hypersensitivity reaction? What are examples?

Answer 1

Also called “immediate hypersensitivity.” Occurs after a person has been exposed to allergen and has developed antibodies. Is IgE mediated. Examples include anaphylaxis and allergic rhinoconjunctivitis.

Question 2

What is Type IV hypersensitivity reaction? What are examples?

Answer 2

Also called “delayed hypersensitivity.” Requires prior desensitization. Initiated by mononuclear leukocytes–mediated by T cells and monocytes/macrophages rather than by antibodies. Examples include contact dermatitis, allograft rejection, poison ivy, TB test.

Question 3

What is type II hypersensitivity reaction? What are examples?

Answer 3

Cytotoxic hypersensitivity reactions-example is drug hemolytic anemia

Question 4

What is type III hypersensitivity reaction? What are examples?

Answer 4

Immune complex-example is serum sickness.

Question 5

How can you differentiate between Rocky Mountain Spotted Fever and meningococcemia?

Answer 5

onset of meningococcemia is generally quicker, within a couple of days versus longer period for RMSF

Question 6

What is active immunity? How is it acquired?

Answer 6

Resistance developed in respose to an antigen and characterized by an antibody produced by the host–vaccinations

Question 7

What is passive immunity? How is it acquired?

Answer 7

Immunity coferred by an antibody produced in another host-from mother to baby or through admin of IG