GI/hepatic Flashcards
What are potential complications of prolonged PPI use?
vitamin B12, calcium, magnesium, and iron malabsorption; increased fracture risk, increased c dif risk
What type of ulcer is caused by H. pylori?
duodenal
When is fecal H. pylori testing helpful?
to check for eradication after treatment
When are the following likely elevated: neutophils/bands lymphocytes monocytes eosinophil basophil
bacteria virus debris allergens, parasites anaphylaxis
What is normal % of neutrophils lymphocytes monocytes eosinophils basophils
60% 30% 6% 3% 1%
What is Markle’s sign?
Pt stands on toes and lets weight fall quickly to heels. Is positive if abd pain increases of peritoneal inflammation
What is Blumberg’s sign?
Deep palp of area of abd tenderness and rapidly releasing-abd pain is worse with release “rebound tenderness” indicating peritoneal inflammation
What is Murphy’s sign?
Painful arrest of inspiration triggered by palpation of edge of inflamed gallbladder
what is obturator and psoas sign?
obturator is when supine with knees flexed, rotate knee/hip. psoas is on side, pull back–indicative of appendicitis
What are symptoms of duodenal ulcer?
intermittent upper abd pain 2-3hours after eating-relieved with foods, antacids
When is a “left shift” likely to occur?
severe bacterial infection
Differentiate between ALT and AST in terms of half-life and when they normally rise. Which is more sensitive to liver damage?
ALT long half life and take some time to rise and fall. Often increases in all hepatitis infections or other industrial chemical associated hepatitis. AST has shorter half life and rises and falls quickly. Increases In ETOH related injury as well as statin-related. ALT is more sensitive
How is duodenal ulcer treated?
Abx-clarythromycin
COX-1 contributes to
maintaining gastric protective mucosal layer
COX-2 contributes to
inflammatory process
