Immunology 3

Question 1

Do eosinophils present antigens

Answer 1

NO

Question 2

What cells are APCs

Answer 2

Dendritic cells
Macrophages

Question 3

What are the 2 types of T cells

Answer 3

Helper T cells
Cytotoxic (killer) T cells

Question 4

2 functions of Helper T cells

Answer 4

• Activate macrophages & dendritic cells (APCs)
• Activate cytotoxic T cells & B cells

Question 5

Function of cytotoxic T cells

Answer 5

Kill infected cells

Question 6

What do cytotoxic T cells need

Answer 6

Education & activation

Question 7

What are T cells functional after

Answer 7

After migrating through the lymphatics to the thymus.
Get educated in the thymus as to what’s self & non self

Question 8

Are T & B cells part of innate / adaptive immune system

Answer 8

Adaptive

Question 9

Function of B cells

Answer 9

Make antibodies

Question 10

What do B cells differentiate into & what do these do

Answer 10

Plasma cells, make antibodies

Question 11

What 5 kinds of antibodies do B cells make

Answer 11

• IgM
• IgA
• IgG
• IgE
• IgD

Question 12

What do B cells need to do before able to make antibodies

Answer 12

Talk to CD4 T cells (helper T cells) first.
Turns B cells on to make plasma cells & antibodies

Question 13

Where do memory B cells migrate to & why

Answer 13

To bone marrow for memory

Question 14

Where are IgA antibodies found

Answer 14

Mucosa

Question 15

Where are IgG antibodies found

Answer 15

Blood

Question 16

What are IgE antibodies for

Answer 16

allergies

Question 17

What are IgD antibodies for

Answer 17

Immune development

Question 18

Steps of dendritic cells carrying antigen to lymph nodes

Answer 18

1. Immature dendritic cells reside in peripheral tissue
2. Dendritic cells migrate via lymphatic vessels to regional lymph nodes
3. Mature dendritic cells activate naive T cells in lymphoid organs such as lymph nodes

Question 19

Steps in the lymph nodes of presenting antigens to B cells

Answer 19

1. Antigens enter lymph node visa afferent lymphatics
2. Antigens captured by macrophages & presented to B cells
3. Antigens transported to follicular dendritic cells & presented to B cells
4. B cells replicate to make specific antibodies to them

Question 20

Steps of adaptive immunity

Answer 20

1. Virus infects & replicates in epithelium
2. Dendritic cell activation
3. Dendritic cells tale infection to lymph node
4. T & B cell priming in lymph node (B cell differentiated to Plasma cell, T cell activated)
5. Antibodies & T cells attack virus & virus infected cells