Immunology Flashcards
How do prions cause disease?
Bursting out of brain tissue causing holes
Lysozymes
Enzymes which break down bacterial cell walls
Oils (chemical barriers)
Contains anti fungal and antibacterial properties
Leaves strong smells
Circulatory system
Closed circuit - blood always contained in the vessels
Components - heart,vessels,blood vessels
Function of the circulatory system
Transport nutrients and remove waste from the body via blood
Transport white blood cells around the body
Blood
Components- plasma, RBC,WBC= immune system,platelets
Where are WBC made?
Bone marrow = part of lymphatic system
Lymphatic system
Open circuit
Components - bone marrow, thymus = maturation of T cells, lymph nodes, lymph fluid, WBC
Function of lymphatic system
Transport fluid back to circulatory system
Samples fluid for detection of pathogens
Valves
Prevent backflow of fluid so that lymph moves in one direction
Why NKC?
Virus inside host cell too big for phagocyte > NKC used
Leukocyte
general term for all WBC
Lymphocyte
specific type of WBC involved in the adaptive (specific) immune response
B Cells (lymphocyte)
contains a specific type of antibody on their surface and also recognise non-self antigen on pathogen
what are antibodies?
protein
Prevent viruses binding to receptors that allow them to enter cells.
if viruses cant enter the cells they cant replicate and destroy the host cell
Inhibit viral enzymes involved in viral replication
they cant replicate their DNA they cant make new viruses and they cant destroy host cell
Block transcription and translation of viral proteins.
they cant make new protein coats they cant make new viruses and they cant destroy the host cell
Prevent viruses from leaving host cells
prevents from leaving the host cells
example of natural active
infected with a pathogen
example of natural passive
breast milk
placenta transfer
example artificial active
vaccination
example artificial passive
antivenom
blood type scaffold
Because blood type ______ has A/B/AB/NO antigens
Then the _____ antigens will/will not be recognised as non-self
Therefore, it will/will not initiate a immune response