Immunological Flashcards
secondary immunodefiency caused by
drug induced immunosuppression (chemo), burns, radiation, cirrhosis
leukopenia
low wbc count
side effect of chemo
leukopenia
hiv
immunodefiency resulting from a defiency of t helper cells
- immune system becomes impaired by infection and destruction of CD4 cells
cause of hiv
viremia (large amount of virus in the blood) causing viral dissemination to organs
two types of HIV
HIV 1 and HIV 2
HIV 1 or HIV 2 most common
HIV1
which is more infectious HIV1 or 2
HIV1
5 condition for HIV transmission
- must be a source of infection
- must be a means of transmission
- must be a host that is susceptible to infection
- must be an appropriate route of entry to target cells
- must be sufficient levels of virus to establish infection
how is HIV transmitted
sexual contact
exposure to infected blood
exposure to transplant tissue
perinatal transmission
how is hiv not transmitted
casual family contact
insect bites
sharing dishes
risk for hiv
sexual behaviour
sti
lack of circumcisition
genetic background
risk factors for hiv; sexual behaviour
anal, vaginal, oral, high number of sexual partners, sex during menses
cm of acute hiv
- development of hiv antibodies
- flu like symptoms (fever, swollen lymph glands, sore throat, headache, malaise, diarrhea, muscle and joint pain)
cm of chronic hiv
asymptomatic
aids
acquired immunodeficiency syndrome
a disease of the immune system due to infection with hiv
most advanced stage of hiv
aids
to be diagnosed with aids
person w hiv must have cd4 count less than 200 cells
cm and complications
- Pneumocystis jirovecii pneumonia
- Cryptococcal meningitis
- Cytomegalovirus retinitis
- Mycobacterium avium complex
- Kaposi’s sarcoma
- Influenza virus
can hiv be cured
no
