GI Flashcards
gastritis?
inflammation of gastric mucosa
how is chronic gastritis divided?
autoimmune
diffuse antral
multifocal
autoimmune gastritis
involves body and fundus of stomach
diffuse antral gastritis
affects antrum
multifocal gastritis
diffuse throughout the stomach
gastritis occurs as a result of…
breakdown in the normal gastric mucosal barrier
what does the mucosal barrier do?
protects stomach tissue from autodigestion of HCL and pepsin enzyme
what happens when mucosal barrier is broken?
HCL can diffuse into mucosa
what does HCL diffusing into mucosa lead to?
tissue edema, disruption of capillary walls with loss of plasma into gastric lumen, possibly hemorrhage
drugs that cause gastritis
ASA, NSAIDS, corticosteroid drugs
diet that causes gastritis
alcohol, spicy food
microorganisms that cause gastritis
helicobacter pylori, salmonella, staphylococcus
environment that causes gastritis
radiation, smoking
pathophysiological conditions that cause gastritis
burns, crohns, hernia, physioogical stress, reflux of bile and pancreatic secretions, renal failure, sepsis, shock
other factors that cause gastritis
- endoscopy
- nasogastric suction
- psychological stress
symptoms of acute gastritis
anorexia, N & V, epigastric tenderness, fullness feeling , hemorrhage
symptoms of chronic gastritis
same as acute
diagnostics for acute gastritis
hx of drug and alcohol use
diagnostics for chronic gastritis
endoscopic exam with biopsy, CBC
if vomiting accompanies acute gastritis, what is prescribed?
bed rest, NPO, IV fluids
what drugs are given for N & V in acute gastritis?
antiemetics
in those with acute gastritis and hemorrhage is likely, what do we do?
VS frequently, check vomit for blood
what drugs are given to relieve symptoms of abdominal discomfort in those with acute gastritis?
antacids
treatment of chronic gastritis focuses on?
eliminating the cause such as cessation of alcohol and drugs
diet of those with chronic gastritis
non irritating, 6 meals a day, use of antacid after meals, smoking contraindicated
what PUD?
erosion of the GI mucosa
what does PUD result from?
digestive action of HCL and pepsin
how are acute ulcers characterized?
superficial erosion and minimal inflammation
whats more common, acute or chronic ulcers?
chronic
what type of environment do peptic ulcers develop in?
acidic
where are gastric ulcers commonly found?
lesser curvature close to the antral junction
whats more common, gastric or duodenal ulcers?
duodenal
whats stress related mucosal disease?
condition of acute ulcers that develop after a major insult such a trauma or surgery