Immunohistochemical Stains Flashcards

1
Q

Chromogranin and synaptophysin

A

Neuroendocrine cells

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2
Q

Cytokeratin

A

Epithelial cells

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3
Q

Desmin

A

Muscle

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4
Q

GFAP

A

Neuroglia (astrocytes, Schwann cells, oligodendrocytes)

Astrocytoma & Glioblastoma

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5
Q

Neurofilament

A

Neurons

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6
Q

PSA

A

Prostatic epithelium

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7
Q

S-100

A

Neural crest

Melanoma, Schwannoma, Langerhans cell histiocytosis

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8
Q

TRAP+

A

Hairy Cell Leukemia

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9
Q

Vimentin

A

Mesenchymal tumor
sarcoma, meningioma, RCC, endometrial carcinoma

(Fibroblasts, endothelial cells, macrophages)

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10
Q

P-glycoprotein

A

aka MDR1
adrenocortical carcinoma classically
(also colon, liver)

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