genes Flashcards
1
Q
ALK
A
Receptor Tyrosine Kinase;
Lung Adenocarcinoma
2
Q
BCR-ABL
A
Non-receptor Tyrosine Kinase;
CML, ALL
3
Q
BCL-2
A
Anti-apoptotic molecule;
Follicular and Diffuse Large B-Cell Lymphoma
4
Q
BRAF
A
Serine/ Threonine Kinase;
Melanoma, NHL, Papillary thyroid carcinoma, Hairy cell Leukemia
5
Q
c-KIT
A
Cytokine receptor;
GIST gastrointestinal stromal tumor
6
Q
C-MYC
A
TF;
Burkitt Lymphoma t(8,14)
7
Q
HER2/neu (c-erbB2)
A
Receptor tyrosine kinase;
Breast and Gastric carcinomas
8
Q
JAK2
A
Tyrosine kinase;
Chronic myeloproliferative disorders (PCV)
9
Q
KRAS
A
GTPase;
colon cancer, lung cancer, pancreatic cancer
10
Q
L-MYC1
A
TF;
Lung tumor
11
Q
N-MYC
A
TF;
Neuroblastoma
12
Q
RET
A
Receptor Tyrosine Kinase;
MEN2A & MEN2B, papillary thyroid carcinoma