Immunohematology

Question 1

Can coat red cells and lead to removal by macrophages (extravascular hemolysis)

Answer 1

Warm Antibodies

Question 2

Very efficient at fixing complent and causes intravascular hemolysis

Answer 2

Cold antibodies

Question 3

Core backbone of all antigens in ABO blood group

Answer 3

Paragloboside

Question 4

Paragloboside with a fucose which is a precusor to the A and B antigen

Answer 4

H antigen

Question 5

Addition of NAG to H antigen

Answer 5

A antigen

Question 6

Addition of galactose to H antigen

Answer 6

B antigen

Question 7

Testing for antigens on red cells

Answer 7

Forward typing

Question 8

Patients serum is given (contains AB) versus commercial A1 and B cells

Answer 8

Reverse typing

Question 9

Blood type without antibodies

Answer 9

AB

Question 10

Seen in Group A patients with exposure to gram (-) bacteria

Answer 10

Acquired B phenotype

Question 11

Lacks the H gene and forward typing appears type O

Answer 11

Bombay (Oh) phenotype

Question 12

D antigen protein structure is altered

Answer 12

D Mosaic/D Variant phenotype

Question 13

Can detect IgG on RBC (IgG vs IgG) in-vivo

Answer 13

Coomb’s Reagent

Question 14

Detects AB to RBC antigen present in patients serum - in-vitro

Answer 14

Indirect Coomb’s Test

Question 15

Detects AB in the patient’s serum that may destroy donor RBC

Answer 15

Major crossmatch

Question 16

Detects AB in donors serum which may react to recipient Ag

Answer 16

Minor crossmatch