Basic Hematology

Question 1

Normal amount of Hemoglobin

Answer 1

Hb/100ml of blood
=14-18g/100ml (men)
=12-16g/100ml (women)

Question 2

Cause for an increase in hemoglobin

Answer 2

Increase WBC count
Smoking
Dehydration

Question 3

Normal RBC count

Answer 3

4. 5-6.0 x 10^3/L (men)

4. 0-5.5x10^3/L (women)

Question 4

Normal Hematocrit

Answer 4

40-54% (men)

37-47% (women)

Question 5

Which Indices is/are increased in Macrocytosis and decrease in microcytosis

Answer 5

MCV and MCH

Question 6

Which Indices is/are increased in Spherocytosis?

Answer 6

MCHC

Question 7

Information that can be obtained in PBS

Answer 7

• estimation of amount of Hb
• size and shape of RBC
• see abnormal cells
• estimation of platelet count

Question 8

Reticulocytes appear on PBS as…

Answer 8

• macrocytic

- polychromatophilic RBC

Question 9

Normal WBC count

Answer 9

5-10 x 10^3/L

Question 10

From highest to lowest WBC

Answer 10

Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophil

Question 11

Use of bone marrow aspiration

Answer 11

Confirm diagnosis of:

• megaloblastic anemia
• multiple myeloma
• leukemia
• bone marrow hypoplasia

Question 12

Variation in sizes seen on PBS

Answer 12

Anisocytosis

Question 13

Variation in shape seen on PBS

Answer 13

Poikilocytosis

Question 14

Increased central pallor ratio

Answer 14

Hypochromia

Question 15

Variation in central pallor

Answer 15

Anisochromia

Question 16

With sharp-pointed projections

Answer 16

Acanthocytes

Question 17

With spiny projections

Answer 17

Burr cell

Question 18

Seen in G6PD deficiency

Answer 18

Bite cell

Question 19

RBC fragment still present on peripheral circulation

Answer 19

Schistocyte

Question 20

Smaller than normocytes; Corpuscles are well filled with hemoglobin; hyperchromic

Answer 20

Spherocyte

Question 21

Found in thalassemia, liver disease and post-splenectomy

Answer 21

Target cell

Question 22

Seen in myelodysplasia

Answer 22

Tear drop cell

Question 23

With rectangular central pallor

Answer 23

Stomatocyte

Question 24

Stacking of cells

Answer 24

Rouleaux Formation

Question 25

Where is Rouleaux formation seen?

Answer 25

Hypergammaglobulinemia and Multiple myeloma

Question 26

With refractive granules close to the periphery; also seen in G6PD deficiency

Answer 26

Heinz bodies

Question 27

An index of bone marrow production of mature RBC

Answer 27

Reticulocytosis

Question 28

A measure of anisocytosis

Answer 28

Red Blood Cell Distribution Width (RDW)