Immunodeficiency Images Flashcards
1
Q
What does this flow cytometer of an infant show? What do CD3 and CD19 represent? What disease?
A
CD3 = T Cells
CD19 = B Cells
Shows low B and T cells
Severe Combined Immunodeficiency
2
Q
What is missing in the patient? Y axis is MHC class II
A
Patient is lacking B cells that are positive for MHC Class II
Bare lymphocyte syndrome
Deficient in CD4 Cells but still have T cells
Deficienct in gammaglobulins
3
Q
What does this show? What diagnosis?
A
Many T cells, very few B cells
X-linked Agammaglobulinemia
4
Q
What does this show? What disease? Remember CD154 is CD40L!
A
Presence of T cells but shows none with CD40L so they can’t be activated
Will not get class switching
Hyper IgM
