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HEME Micro & Immuno > Immunocompromised HPR > Flashcards

Immunocompromised HPR Flashcards

1
Q

cough in M. tuberculosis vs. Pneumocystis jiroveci

A

Tub–> PRODUCTIVE cough;

P. jiroveci–> non-productive

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2
Q

Clinical signs of pneumonia are usually absent despite infiltrates on x-ray

A

Pneumocystis jiroveci

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3
Q

septate hyphae and conidia on the conidiophore

A

aspergillus fumigatus

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4
Q

pts with asthma and allergies–>

A

aspergillus fumigatus

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5
Q

Eosinophila and allergic aspergillosis (pulmonary infiltrates)

A

aspergillus fumigatus

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6
Q

fungus ball seen on xray–>mycelial masses

A

aspergillus fumigatus

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7
Q

hemoptysis due to FISTULAS

A

aspergillus fumigatus

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8
Q

Filamentous fungus; Normal flora of rice, bean

A

Fusarium solani

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9
Q

Medication-related Immunodeficiency

Corticosteroids–> bacteria

A

All bacteria, particularly M. tuberculosis

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10
Q

Medication-related Immunodeficiency

Corticosteroids–>Fungi

A

Pneumocystis jiroveci, Aspergillus f, Fusarium solani

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11
Q

Medication-related Immunodeficiency

Corticosteroids–> parasite

A

Strongyloides stercoralis

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12
Q

Medication-related Immunodeficiency:

TNF-α inhibitors

A

Listeria monocytogenes

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13
Q

Medication-related Immunodeficiency:

Rituximab (mAb to CD20)

A

Babesia microti

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14
Q

pulmonary and peripheral eosinophilia

A

Strongyloides stercoralis

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15
Q

transient, raised, red, serpiginous lesions over buttocks and lower back

A

Strongyloides stercoralis

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16
Q

HBV reactivation

A

Rituximab

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17
Q

TB reactivation

A

TNF-α inhibitors

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18
Q

pate, contaminated milk, soft cheeses, coleslaw

A

Listeria monocytogenes

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19
Q
  • Internalin
  • Listerolysin O (LLO)
  • Propels through cytosol via actin polymerization
A

Listeria monocytogenes

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20
Q

Clay-colored bowel movements;

Dark urine

A

Hepatitis B Virus

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21
Q

Asplenic patients

A

Encapsulated (S. pneumo; H. influ; N. menin)
Babesia!!
Capnocytophaga canimorsus

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22
Q

Streptococcus pneumoniae

Haemophilus influenzae

Neisseria meningitidis

A

Encapsulated;
Asplenic Patient;
Humoral Immunodeficiency

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23
Q

Capnocytophaga canimorsus found in what patient pop?

A

asplenic

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24
Q

alpha-hemolysis (green zone around colonies)

A

Streptococcus pneumoniae

Viridans Streptococci

25
Q

Capsule is anti-phagocytic

• IgA protease

A

Streptococcus pneumoniae

26
Q

Meningitis in very young (

A

Streptococcus pneumoniae

27
Q

causes MOPS: Meningitis, otitis media,pneumonia and sinusitis

A

Haemphilus influenzae

28
Q

hocolate agar containing hematin (factor X) and NAD (factor V)

A

Haemphilus influenzae

29
Q

Gun metal gray, hemorrhagic, necrotic patches

A

Neisseria meningitidis

30
Q

Erythematous macules initially

Petechiae and purpura

A

Neisseria meningitidis

31
Q

Culture on Thayer-Martin or chocolate agar

A

Neisseria meningitidis

32
Q

Digital necrosis

A

Capnocytophaga canimorsus

33
Q

Gram-negative of oropharynx of canines

A

Capnocytophaga canimorsus

34
Q

Early post-transplant period (2 and 6 months):

Opportunistic pathogens:

A

Pneumocystis jiroveci,
Aspergillus fumigatus
Cryptococcus neoformans

35
Q

Early post-transplant period (2 and 6 months):

Reactivation of latent pathogens:

A

CMV;
Varicella zoster virus;
BK virus;
Toxoplasma gondii

36
Q

> 6 months post-transplant:

A

encapsulated bacteria.

37
Q

Encapsulated yeast-like fungus

A

Cryptococcus neoformans

38
Q

Meningitis in immunocompromised patients (e.g. early post transplant)

A

Cryptococcus neoformans

39
Q

Bone marrow transplants = interstitial pneumonia leading cause of death

A

Cytomegalovirus

40
Q

low birth weight, microcephaly, chorioretinitis

• Fetal damage most likely in 1st trimester

A

Cytomegalovirus

41
Q

Hemorrhagic cystitis in bone marrow transplants

42
Q

Polyomavirus family

• Small double-stranded DNA virus with icosahedral capsid

43
Q

Virus to kidneys and UT - persists for the life

44
Q

Consuming raw or undercooked, contaminated meat

A

Toxoplasma gondii

45
Q

Ingesting water, soil, vegetables, or anything contaminated with feces of an infected animal (particularly cats)

A

Toxoplasma gondii

46
Q

Pseudomonas aeruginosa desc.

A
  • Aerobic, Gram-negative bacillus

* Polar flagella for motility

47
Q

Widespread in moist environments

A

Pseudomonas aeruginosa

48
Q

Grows as golden, β-hemolytic colonies on blood agar

A

Staphylococcus aureus

49
Q

Coagulase-negative gram-positive cocci that Forms biofilms on catheters and indwelling devices

A

Staphylococcus epidermidis

50
Q

White piedra – soft, pale

nodules on hairs of scalp and body

A

Trichosporon asahii

51
Q

Subcutaneous lesions from injury following “traumatic implantation” by contaminated splinters or plant thorns

A

Scedosporium prolificans

52
Q

Thin, pleomorphic, Gram-negative bacillus

A

Legionella pneumophila

53
Q

WATER SOURCES such lakes, riverbanks

A

Legionella pneumophila

54
Q

Herpesviridae, dsDNA

Varicella & shingles

55
Q

a-hemolytic gram + cocci in chains Dental carries Subacute endocarditis

A

Viridans Streptococci

56
Q

Anamorphic yeast
White piedra
Invasive infection (lung, kidneys, spleen)

A

Trichosporon Asahii

57
Q

Filamentous fungus

SubQ lesions after implantations – thorns/splinters

A

Scedosproium prolificans

58
Q

Dimorphic fungus, no yeast phase-barrel hyphae
Harsh environments
Chronic pulmonary form – cavity + relapse

A

Coccidioides Immitus

59
Q

Progressive pulmonary disease similar to that of pulmonary TB  starts off w/ dyspnea and non-productive cough, eventually moving to productive cough

A

Histoplasma Capsulatum

HEME Micro & Immuno (11 decks)

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