Immuno - Immune Responses (Infections in immunodeficiency)

Question 1

In general, what kinds of infections are associated with B-cell deficiencies?

Answer 1

B-cell deficiencies tend to produce recurrent bacterial infections

Question 2

In general, what kinds of infections are associated with T-cell deficiencies?

Answer 2

T-cell deficiencies produce more fungal and viral infections

Question 3

What bacterial infection occurs when patients have no T cells?

Answer 3

Sepsis

Question 4

What bacterial infections occur when patients have no B cells?

Answer 4

Encapsulated: Streptococcus pneumoniae, Haemophilus influenzae type B, Neisseria meningitidis, Escherichia coli, Salmonella, Klebsiella pneumoniae, group B Strep (SHiNE SKiS)

Question 5

What 4 bacterial infections occur when patients have no granulocytes?

Answer 5

Staphylococcus, Burkholderia cepacia, Serratia, Nocardia

Question 6

What bacterial infection occur when patients have no complement?

Answer 6

Neisseria (no membrane attack complex)

Question 7

What 5 viral infections occur when patients have no T cells?

Answer 7

CMV, EBV, JCV, VZV, chronic infection with respiratory/GI viruses

Question 8

What 2 viral infections occur when patients have no B cells?

Answer 8

Enteroviral encephalitis, Poliovirus (live vaccine contraindicated)

Question 9

What viral infections occur when patients have no granulocytes?

Answer 9

N/A

Question 10

What viral infections occur when patients have no complement?

Answer 10

N/A

Question 11

What 2 fungal/parasitic infections occur when patients have no T cells?

Answer 11

Candida, PCP

Question 12

What fungal/parasitic infection occurs when patients have no B cells?

Answer 12

GI giardiasis (no IgA)

Question 13

What 2 fungal/parasitic infections occur when patients have no granulocytes?

Answer 13

Candida, Aspergillus

Question 14

What fungal/parasitic infections occur when patients have no complement?

Answer 14

N/A