Immuno

Question 1

Innate VS Adaptive Immunity

Answer 1

Question 2

Describe neutrophils.

Answer 2

Location: Blood
Life span: 48-72 hrs
Function: antimicrobial
Action: phagocytosis, degranulation, trap formation

Question 3

Describe eosinophils.

Answer 3

Location: Blood, GI tract, airways
Life span: Days to weeks
Function: antiparasitic, antiviral, allergy
Action: degranulation, phagocytosis

Question 4

Describe basophils.

Answer 4

Location: blood
Life span: days
Function: inflammation
Action: degranulation

Question 5

Describe mast cells.

Answer 5

Location: tissue (CT around vasculature/nerves) & lamina propria of mucosa
Life span: weeks to months
Function: immune surveillance, mediator, amplifies inflammation & allergy
Action: detects threats, degranulation (vasoactive amines) or synthesis of lipids & cytokines

Question 6

Describe macrophages.

Answer 6

Location: peripheral tissue
Life span: months
Function: immune surveillance, antimicrobial, antigen presentation
Action: detect threats, release inflammatories, phagocytosis

Question 7

Describe dendritic cells.

Answer 7

Location: tissues
Life span: months
Function: immune surveillance, antigen presentation
Action: detect threats, release inflammatory, endocytosis & phagocytosis

Question 8

Describe NK cells.

Answer 8

Location: blood, spleen
Life span: months
Function: destroy virally infected or abnormal (tumor) cells
Action: cytotoxic granules

Question 9

Describe lymphocytes.

Answer 9

Location: blood tissues, secondary lymphoid organs
Life span: weeks, months, years (memory cells)
2 types = T & B cells

Question 10

Describe cytokines.

Answer 10

-proteins
-cell growth, activation
-interleukins = communication
-chemokines = chemotaxis

Question 11

Describe the complement system.

Answer 11

-plasma proteins that acts as signaling molecules to recruit immune cells to inflammatory sites
-attacks cell membrane = cell death
-classical (adaptive), lectin, alternative pathways