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Pharmacology > Immunizations > Flashcards

Immunizations Flashcards

1
Q

IgA

A

Mucous, tears, breastmilk

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2
Q

IgD

A

Part of B cell receptor. Activates basophils and mast cells

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3
Q

IgE

A

Protects against parasitic worms. Responsible for allergic reactions

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4
Q

IgG

A

Secreted by plasma cells. Can cross placenta

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5
Q

IgM

A

Early stages of immunity

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6
Q

Passive immunity

A

Transfer of immunities via antibodies from person to person. Maternal antibody to infant. Wanes 4-12 months after birth

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7
Q

Active immunity

A

Stimulation of own immune system. Relies on immunologic memory. Occurs from natural infection or vaccination

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8
Q

Live attenuated vaccines

A

Contains live, weakened organisms

MMR, varicella, polio (sabin) adenovirus, influenza (inhaled), rotavirus, rotavirus

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9
Q

Positives and negatives of live attenuated vaccines

A

single dose provides long-lasting immunity. Contraindicated in pregnancy and immunocompromised; adverse reactions similar to actual disease

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10
Q

Whole inactivated vaccines

A

Hep A, Rabies, Influenza (IM), whole cell pertussis

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11
Q

Positive and negatives of inactivated vaccines

A

Safe in pregnancy and immune compromised states.

Multiple doses or boosters needed

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12
Q

Fractional inactivated vaccines

A

Portion of pathogen

Polysaccharide vaccines like PPV23, acellular pertussis, meningitis, influenza, hep B, HPV

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13
Q

Toxoids

A

Inactivated bacterial toxins

Tetanus, diphtheria

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14
Q

Adjuvants

A

Substance that enhances immune response to the antigen. Aluminum is the only approved adjuvant. Used in Hep B/A, DTaP, DT, Hib, HPV

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15
Q

Pediarix

A

DTaP, Hep B, IPV

*we always give the Hep B vaccine in the newborn (pediatric) nursery

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16
Q

Proquad

A

MMR + varicella

17
Q

Kinrix

A

DTaP + IPV

18
Q

Pentacel

A

DTaP+IPV+Hib

*Think Pentagon is like a like Hub (HiB)

19
Q

Comvax

A

Hib + HepB

20
Q

Twinrix

A

Hep A and Hep B

21
Q

True or false

Shortening the interval between doses does not interfere with immune response

A

False. It does. However, lengthening the interval does not diminish effectiveness.

22
Q

True or false: A immunocompromised patient can receive an inactivated vaccine

A

true

23
Q

True or False. You can’t receive a vaccine if you are breastfeeding, need TB skin testing, or are getting to many vaccines at one time

A

False

24
Q

What trimester should a pregnant person receive the TDaP vaccine

A

3rd trimester

25
Q

List some people who should not be given a LAIV

A

Asplenia, HIV, immunocompromised (or close contacts), cochlear implant, those who received influenza antiviral medication in past 48 hours, previous serious reaction to influenza vaccine

26
Q

CD4 count has to be above this to receive the MMR

A

200 for at least 6 months

Pharmacology (4 decks)

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