Immunity: Components of Specific/Acquired Immunity Flashcards
Response found in vertebrates following exposure to a particular antigen
Specific immunity
First exposure to a particular antigen
Primary immune response
On future contact with the same agent, a rapid and more intense response occurs
Secondary/memory/anemic response
Major cell types involved in specific/acquired immunity
Lymphocytes (B ANNNND T)
These cells are important in the induction of specific immunity by acting as antigen presenting cells (APCs)
- Macrophages
- Dendritic cells
Time interval between first exposure and pre-committed lymphocyte activation
Induction phase
Activation of cells with specific receptors
Specificity
Each one of these cells contains antigens specific recognition molecules on the plasma membrane
B & T cells
B & T cells with antigens specific recognition specific receptors are activated and cells divide to produce more daughter cells with the same antigenic receptor
Clonal selection
Production of a clone of cells from original cells activated that provide memory cells for the secondary/anemnestic response
Immunologic memory
No response to cells and tissues in the body or self antigens
Tolerance
Most specific immune responses enhance what are considered to be _____
Non-specific
This type of naturally acquired immunity involves recovery from an infection
Active
This type of naturally acquired immunity involves transplacental passage of antibodies or breast milk
Passive
This type of artificially acquired immunity involves vaccination
Active
This type of artificially acquired immunity involves immunoglobulin injections
Passive
Production of circulating antibodies or immunoglobulins by plasma cells which are formed from activated B lymphocytes
Humoral immunity
What are formed from activated B lymphocytes?
- Antibodies
- Immunoglobulins
Functions of Ab
- Neutralizes toxins and viruses
- Opsonizes bacteria
- Tags organisms for destruction
Activation of specific sets of T-lymphocytes which inhibits organisms such as fungi, parasites, and intracellular bacteria. Also kills virus infected cells and tumor cells
Cell-mediated immunity
