Immunity cell recognition and immune system Flashcards
Explain why antibody A attaches only to the protein found in species of
Plasmodium (genus)
-specific tertiary structure
- complimentary to binding site of protein
on the Eliza test what is the point of the control antibody
- prevent false negative results
- show antibody has not bound to antibody in blood
has a person tested positive for malaria?
- no colour change first antibody for one variant
-colour change for next variant
-colour change to test for false negative result
-person is infected with malaria
- infected with variant 2
- as colour dye causes colour change
-not infected with variant one as there is no colour change
how does micro mRNA bind to mRNA which codes for cell death and what are the effects
-micro mRNA has complimentary base pairs to mRNA, binding to mRNA
- mRNA can no longer be read by ribosome
- proteins not translated
-proteins which cause cell death are not produced so increased cell division
when is a protein made
translation
when is mRNA made
transcription
A mutation of a tumour suppressor gene can result in the formation of a tumour.
-forms non functioning proteins, inactivating/turning off gene
-uncontrolled cell division
when a gene produces non functioning proteins what is the gene called?
turned off/ inactivated
Using your knowledge of the structure of the cell-surface membrane, suggest how
LDL enters the cell.
-LDL specific tertiary structure binds to cell
- moves into cell via channel protein
Suggest two reasons why the percentage of infants vaccinated decreased
-fewer cases
- fear of side effects