Immunity Flashcards
Stage of HIV infection with the following clinical manifestations: high viral load, decreased CD4+, and a high transmission potential.
acute retroviral syndrome
A deadly, sexually transmitted disease caused by the human immunodeficiency virus, a retrovirus
AIDS
Cells of the immune system that are targeted by the HIV virus
CD4+ helper T cells
A coreceptor that allows the HIV virus to attack microphages
chemokine receptor
The stage if HIV infection that occurs after the brief early infection episode, in which the individual may remain asymptomatic for months and years and the virus continues replicating, but not as fast as during the acute phase.
clinical latency or chronic HIV infection stage
The virus GP120 must attach to this receptor in order to attach to the T cells
CXCR4
The second part of the life cycle: the joining of the virus protein and the CD4+ membrane which then allows entry
fusion
Substance on the outer surface of the HIV virus that binds to the CD4+ on dendritic cells
glycoprotein 120
Vaccines that are made from whole or fractions of viruses or bacterial antigens or the toxin produced by the bacteria antigens or the toxin produced by the bacteria
inactivated
A viral enzyme that allows the viral DNA to become integrated into the CD4+ cells own DNA
integrase
Vaccines created from weakened wild viruses or bacteria that can replicate without causing disease. They can create an almost identical immune response as active infection.
live
The enzyme that converts the viral RNA to DNA
reverse transcriptase
Immune complex mediated type of hypersensitivity, in which circulating antigen-antibody complexes accumulate and are deposited in the tissue. This accumulation triggers the complement system, causing local inflammation and increased vascular permeability, so more complexes accumulate
type 3 hypersensitivity
Cell mediated hypersensitivity, which involves a delayed processing of the antigen by the macrophages. Once processed, the antigen is presented to the T cells, resulting in releasing in the release of lymphokines that cause inflammation and antigen destruction
Type 4 hypersensitivity