Immunity

Question 1

What does the complement system do (basic)?

Answer 1

Helps trigger phagocytic cells and help the antibodies do their jobs.

Question 2

Cytokines

Answer 2

Signaling proteins secreted by immune cells to recruit other immune cells.

Includes interferons, interleukins, growth factors

Question 3

Spleen

Answer 3

Filters blood-borne pathogens. Makes WBCs

Question 4

Bone marrow

Answer 4

Where b-cells are made and mature
Makes t-cells

Question 5

Thymus

Answer 5

Where T-cells mature

Question 6

Active vs passive immunity

Answer 6

Active: developed by own body.
Long-lasting. Requires TIME.

Passive: outside source.
Short-term. IMMEDIATE.

Question 7

Natural active vs induced active

Answer 7

N: sick w/flu, now immune
I: vaccine

Question 8

Natural passive vs induced passive

Answer 8

N: breastfeeding

I: immunoglobulins (gamma globulins)

Question 9

Hypersensitivity: type I

Answer 9

Anaphylactic - IgE & basophils

Anaphylaxis, allergies
Asthma
Hay fever

Question 10

Hypersensitivity: type II

Answer 10

Cytotoxic - IgM & IgG

Blood transfusion rxns

Question 11

Hypersensitivity: type III

Answer 11

Immune-complex - IgG & IgM & sometimes IgA-antigen Ab complex

Autoimmune
Lupus, arthritis, type 1 diabetes, Chrohns

Question 12

Hypersensitivity: type IV

Answer 12

Delayed hypersensitivity- Tcells delayed

TB skin test
Transplant rejection

Question 13

Humoral vs cell-mediated immunity

Answer 13

H: B-cells w/ antibodies. Antigens float in the blood. Cells divide into plasma or memory cells.

Cell: T-cells with killer/cytotoxic t-cells. Antigens on the surface of infected cells. Part of delayed type IV hypersensitivity.

Question 14

What immunoglobulin crosses the placenta? What is in breast milk?

Answer 14

Placenta: IgG
Breastmilk/colostrum: IgA

Question 15

What does pregnancy do to the immune system?

Answer 15

Suppresses immunity!