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Immunisation and viral disease > Immunisation > Flashcards

Immunisation Flashcards

1
Q

What is passive immunisation?

A

Transfer of pre-formed antibodies to a susceptible individual giving temporary protection from infection

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2
Q

What is natural passive immunisation

A

mum to baby via placenta and breast milk

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3
Q

What is a live attenuated immunisation

A

Vaccines usins a live wakened form of a pathogen

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4
Q

WHat are the pros of live attenuated vaccines

A

Better immune response, as the pathogen more closely resembles the vaccine

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5
Q

What are the cons of live attenuated vaccines

A

Potential for reversion for virulence, and a sustained vaccine strain infection

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6
Q

Give some examples of live attentuated vaccines

A

BCG, MMR, varcella zoster, rotavirus and others

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7
Q

What is inactivated whole cell immunisationj

A

A pathogen killed by chemical/physical processes

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8
Q

Give examples of inactivated whole cell vaccines

A

Hep A, rabies

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9
Q

What is subunit recombinant protein vaccination

A

A specific viral protein produced in a heterologous expression system

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10
Q

Name subunit recombinant protein vaccines

A

Hep B, Papillomavirus

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11
Q

What are subunit chemically purified vaccines

A

Certain components of a pathogen purified for use in a vaccine

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12
Q

name subunit chemically purified vaccines

A

Acellular pertussis, or influenza

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13
Q

What are polysaccharide vaccines

A

Purified bacterial polysaccharide

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14
Q

name some polysaccharide vaccines

A

Some meningococcal and pneumococcal vaccines

Salmonella

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15
Q

What are conjugated polysaccharide vaccines

A

Purified bacterial polysaccharides linked to a protein

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16
Q

Name some conjugated polysaccharide vaccines

A

Same as polysaccharide vaccines

17
Q

What are adjuvants

A

Agents stimulating the immune system

18
Q

Why are vaccines used post-exposure

A

immunoglobulins and vaccines can be given to reduce chance of developing a disease, or reducing disease activity should it occur

19
Q

What are common adverse effects of vaccination

A

Local reactions like pain, swelling and redness, systemic effects include fever, headache and malaise

Immunisation and viral disease (3 decks)

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