Immune Tissue Hypersensitivity

Question 1

What type of antigen does type 4 HS recognize?

Answer 1

Soluble and Insoluble

Question 2

What effector antibody does type 3 HS use?

Answer 2

IgG

Question 3

Four downstream type 1 HS manifestations

Answer 3

1. Wheal and Flare
2. Acute Rhinitis
3. Anaphylaxis
4. Mast Cell activation

Question 4

Four downstream Type 4 HS manifestations

Answer 4

1. Induration/ Tuberculin Rxn via Th1/Macro
2. Contact Dermatitis (shit haptens)
3. Chronic Asthma//Rhinitis
4. Graft Rejection

Question 5

What effector antibody does type 2 HS use?

Answer 5

IgG

Question 6

What effectors does type 4 use?

Answer 6

T-helpers and CTLs

Question 7

What type of antigen does type 2 HS recognize?

Answer 7

Non-souble; Either Cell-Antigen or Cell-Receptor complexes

Question 8

Four downstream type 3 HS manifestations

Answer 8

1. Arthus Reaction
2. Serum Sickness
3. Complex build up in joints/capillary beds
4. Activate complement and phagos via Fc

Question 9

Four downstream type 2 HS manifestations

Answer 9

1. Drug Allergies
2. Chronic Urticartia
3. RBC ABO rejection
4. Complement/NK/Phago activation

Question 10

What type of antigen does type 3 HS recognize?

Answer 10

Soluble

Question 11

What type of Antigen does type 1 HS recognize?

Answer 11

Soluble

Question 12

What are the four types of G&C Tissue Hypersensitivities?

Answer 12

1. IgE Immediate Hypersensitivity
   .2. IgG Non-soluble/Cell-Surface Mediated
2. IgG Soluble Complex Remover
3. T-cell Delayed Hypersensitivity

Question 13

What effector antibody does type 1 HS use?

Answer 13

IgE