immune system modulation Flashcards
drug classes that modify immune function are
vaccines
immunostimulants
immunosuppressants
therapeutic action of vaccines
expose clients to modified, harmless pathogen or its toxoid
immune response within following weeks or months
b cells are formed
active immunity achieved
if challenged by pathogen, large quantities of antigen are quickly produced
what is active immunity?
immune system stimulated to produce antibodies
exposure to antigen produces active immunity. Vaccines boost antibody production, produces active immunity
what is passive immunity?
passed between people
preformed antibodies
who are passive vaccines given to?
those with suppressed immune systems
those who are exposed or high risk of exposure
what are immunostimulants?
immunostimulants are cytokines made through recombinant DNA technology. Cytokines are secreted by immune cells when they are challenged by antigens
these immunostimulants or cytokines boost certain functions of the immune system
immunostimulents
aldesleukin bacille calmette-guerin interferon alfa 2 interferon beta 1a interferon beta 1b oprelvekin peginterferon
interferon alpha 2a
enhances or stimulates immune system to remove antigens, suppress growth of cancer cells, antiviral acivity
primarily used to remove hairy-cell leukemia, chronic hep c infection, malignant melanoma
flu like adverse effects
with prolonged use, immunosupression can occur as can hepatotoxicity and neurotoxicity
immunosuppressents do what?
inhibit immune system
used to treat severe autoimmune disease or prevent tissue rejection following transplantation
TOXIC TO BONE MARROW