Immune system (2-4) Flashcards
Why do Jehovah’s witnesses object to blood transfusions?
biblical verses whish forbod ingestion of blood. eating meat with residual bllod tho is fine.
what is the sacredness of blood?
idea that the life of a being resides in its blood
What about when kids need it and parents refuse?
medical staff can overrule if it means the child wont live.
What have doctors done to try and accomidate these religious wishes>
bloodless surgeries that dont require blood transfusions of other peoples blood to replace lost blood during surgery
advantages of bloodless surgery
quicker recovery, less invasive, and spend less time on ventilators
Advantages/ disadvantages of the use of biomedical research on animal models?
cheap and quick (adv)
hard to have relevance (dis)
what is a surrogate outcome?
a measurable outcome that is not a clinical outcome but might correlate with a clinical outcome
advantages/ diadvantages of surrogate outcome?
ad: cost and time
dis: relevance, it might not ne effective with other diseases
What are case series?
the study of causes and spreads of disease
What are case-control studies? (retrospective studies)
comparing a pop with the disease (case) with a pop without disease (control) and retrospectively comparing the two to determine information
What are cohort studies? (prospective studies)
the following of groups or situations (cohorts) and propectively anaylsisng the sprisk fatcors in each grooup for diseases etc.
What are the 5 aspects of our innate defenses?
barriers, phagocytes, natural killer cells, inflammation, and fever
adaptive defenses (3)
B-cells, helper T cells, cytotoxic T cells
what two for communication?
ctytokine, and antigen presentation
What is a healthy immune system?
can fight off infection
Why is it better to study immune system with respect to a specific disease>
because there is no way to measure whether your immune system is depressed or boosted but certain diseases depress immune system function
In regards to immune system, what research method is mostly used?
surrogate studies
why is cohort studies not often used?
expensive and time-consuming.
What factors are known to weaken immune system function?
malnutrition, shortage of certain minerals, too much work to do, diseases of cells of the immune system, fatigue
regarding research on specific micronutrients, what are the two issues?
1) deficiency effect on immune system?
2) if normal intake, strengthen immune system?
Selenium
low levels- cancer
cofactor for enzymes, one egg is generally enough to satisfy selenium amounts
Vit. A
low levels- higher risks of infectious diseases
roboflavin (vit B2)
confers some resistance to infectious diseases in mice
Vit. B6
deficicency seems to impair the development and differentiation of B cells and T cells from stem cells
Vit. C
deficiency is unknown really. But is needed for immune system so could help with immune system function
Linus Pailing
a chemist who wrote a book on vit C and the common cold
Vit. D
known to be invovled in fighting Mycobacterium tuberculosis. more prone to HIv, and flu if deficient
Vit. E
suuplementation enhanced the antibody response to some vaccinations but not to others.