Immune System Flashcards
What does immune system consist of (4)
Organs (spleen/nodes/bone marrow)
Cells (WBC and friendly bacteria )
Physical barriers (skin and mucous membrane )
Proteins (antibodies)
What’s the first line of defence
Innate (non-specific)
Skin and mucous membranes
Secretions (pH)
Second line defence
Innate non specific
Inflammatory response
Phagocytosis
3rd line
Adaptive (specific)
Humoral response
Cellular response
Examples of first line of response
Skin
Hair
Cilia
Sweat
Vernix
Micro biome
Amniotic membranes
Placenta
Gastric juices
Microbiome and birth
Mode of birth
Place of birth
Antibiotics?
Microbiome and environment
Skin to skin
Contact with others
Hospital vs your bedding
Breastmilk and Microbiome
Beneficial bacteria
Oligosaccharides
Bifidus factors
Lactoferrin
IgA
Lysozyme
Viral fragments
WBC involved in innate immune response
Granulocytes
Monocytes
WBC involved in adaptative immune response
Lymphocytes ( T and B cell)
When is T cell response active from in fetus
End of first trimester
Why more vulnerable to infection in pregnancy
Physiological adaptations in body systems
Increased interventions
Sensitising events recommending anti d prophylaxis
Invasive Procedures
ECV
Antepartum haemorrhage
Abdominal trauma
Termination
Anti D Risks (4)
Blood product risks (hep C)
Intramuscular injection risk
Some may cross placenta (10% of cases, minor anaemia in some babies)
Sensitisation despite
