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Immuno > Immune responses to pathogen groups > Flashcards

Immune responses to pathogen groups Flashcards

1
Q

Innate cell needed for inflammation

A

Macrophage

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2
Q

Mediators needed for inflammation

A

Those that secrete inflammatory cytokines:

  • TNF
  • IL-1
  • IL-6
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3
Q

Effector innate cell needed to remove virus

A

NK cell

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4
Q

Effector innate cell needed to remove IC bacteria

A

Macrophage

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5
Q

Effector innate cell needed to remove EC bacteria

A

Neutrophil

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6
Q

Th subtype needed to promote effector functions in infected tissue - virus

A

Th1

IL-2 helps CD8

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7
Q

Th subtype needed to promote effector functions in infected tissue - IC bacteria

A

Th1

need IFNgamma to form granuloma

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8
Q

Th subtype needed to promote effector fx in infected tisse - EC bacteria

A

Th17
Th1
Need inflam
Phagocytes recruited

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9
Q

Are CD8 needed for host defence against viruses?

A

Yes

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10
Q

Are CD8 needed for host defense against IC bacteria?

A

Not unless bacteria gets into cytosol

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11
Q

Are CD8 needed for host defense against EC bacteria?

A

No

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12
Q

Are Ab needed for host defense against viruses?

A

No, but important for vaccine defense

IgG

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13
Q

Are Ab needed for host defense against IC bacteria?

A

Not crucial

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14
Q

Are Ab needed for host defense against EC bacteria?

A

Yes

IgG

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15
Q

For which is complement needed against? (Only 1)

A

EC bacteria

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16
Q

Innate cell needed for inflammation against yeast

A

Macrophage

17
Q

INnate cell needed for inflammation against helminths/allergies

A

Mast cell

18
Q

Innate mediator needed for inflammation against yeast

A

TNF
IL-1
IL-6

19
Q

Innate mediator needed for inflammation against helminths/allergies

A

HM

20
Q

Effector innate cell needed to remove yeast

A

neutrophils

21
Q

Effector innate cell needed to remove helminths/allergies

A

Eosinophil

mast cell

22
Q

Th subtype needed to promote effector fxns in yeast infection

A

Th17

Need IL-17 to recruit neutrophils

23
Q

Th subtype needed to promote effector fxn in helminth/allergies

A

Th2

Need IL-5 to recruit eosinophils

24
Q

Are CD8 needed against yeast?

A

No (EC)

25
Q

Are CD8 needed against helminths/allergies?

A

No (EC)

26
Q

Are Ab needed for host defense against yeast?

A

No

27
Q

Are Ab needed for host defense against helminths/allergies?

A

Yes
IgE
Note that Tfh & GC required for class switch recombo

Immuno (4 decks)

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