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Patho Exam 2 Spring 2014 > Immune response > Flashcards

Immune response Flashcards

1
Q

What releases arachidonic acid?

A

Bradykinin

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2
Q

What releases arachidonic acid?

A

Bradykinin

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3
Q

What does arachidonic acid release?

A

Prostaglandins
Leukotrienes
Thromboxanes

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4
Q

What cells are involved in humoral immunity?

A

B Cells

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5
Q

What do basophils store?

A

Chemical mediators

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6
Q

What is the job of thromboxanes?

A

Clotting

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7
Q

What is related to leukotriene action?

A

Arthralgia and myalgia

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8
Q

What produces antibodies?

A

Plasma cells

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9
Q

What substance initiates the inflammatory response?

A

Haegman Factor

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10
Q

Function of interleukins?

A

stimulate T and B cells
cause fever, myalgia, arthralgia, slow wave sleep
increase activity of b cells, cytotoxic cells, NK
stimulate the production of more t cells

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11
Q

Major histocompatibility complex

A

Distinguish self from nonself

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12
Q

What is responsible for fever, myalgia, joint pain?

A

Interleukins

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13
Q

What is a type of myelocyte?

A

Basophil

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14
Q

How long does it take to make antibodies?

A

several days

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15
Q

Neoplasms occur when?

A

when mutant cells escape the immune system and multiply

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16
Q

What cells stimulate other cells to be more aggressive?

A

T helper cells

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17
Q

What immunoglobin is the first to be released upon exposure to an antigen?

A

IgM

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18
Q

Full thickness body burns can cause what barriers to be destroyed?

A

Skin & Mucous membranes

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19
Q

How many immunoglobins are there?

A

5

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20
Q

Complement proteins form a ring around an antigen and do what?

A

alter the antigens membrane
release histamine
induce chemostaxis
increase phagocyte activity

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21
Q

Gold salts inhibit what?

A

Phagocytes

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22
Q

NSAIDS inhibit what?

A

Prostaglandins

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23
Q

Salicylates block what?

A

Prostaglandin activity

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24
Q

When can a pt who underwent surgery begin taking aspirin again?

A

1 week (7 day)

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25
Q

How is etanercept given?

A

SQ

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26
Q

What agent is contraindicated for a pt allegic to tartrazine?

A

Aspirin

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27
Q

What is injected into the knee to prevent arthritis?

A

Hyaluronidase

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28
Q

How long does it take for penicillamine to take effect?

A

2-3months

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29
Q

Acute salycilate toxicity signs?

A

Hyperpnea
Excitement
Tetany

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30
Q

When is gold salts contraindicated?

A

DM
HTN
Blood dyscrasias

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31
Q

Celebrex is contraindicated in?

A

Sulfa allergies

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32
Q

Are there drug to drug interactions for interleukins and interferons?

A

No

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33
Q

Which drug causes t cells to be disabled?

A

Muromomab-CD3

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34
Q

What is an adverse effect of monoclonal antibodies?

A

Pulmonary edema

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35
Q

What is an adverse to immune stimulants?

A

flu like symptoms

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36
Q

What is the most common immune suppressant?

A

Cyclosporine

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37
Q

What can you mix cylcosporine with?

A

Orange juice, milk, chocolate milk

38
Q

Immune sera

A

bacterial antibodies in serum

39
Q

Vaccines are available for what biological weapons?

A

Anthrax, smallpox, botulism

40
Q

What do you give immune globulin for?

A

Bite from an animal w/rabies

41
Q

Adverse effects of immunizations?

A

irritability
anorexia
chills
redness at site

42
Q

Vaccines are what type of immunity

A

active

43
Q

Example of passive immunity

A

antibodies injected in host

44
Q

Tx for botulism

A

Immune sera

45
Q

With what does serum sickness occur

A

immune sera

46
Q

Caution for vaccines if pt has what?

A

Febrile

47
Q

What does arachidonic acid release?

A

Prostaglandins
Leukotrienes
Thromboxanes

48
Q

What cells are involved in humoral immunity?

A

B Cells

49
Q

What do basophils store?

A

Chemical mediators

50
Q

What is the job of thromboxanes?

A

Clotting

51
Q

What is related to leukotriene action?

A

Arthralgia and myalgia

52
Q

What produces antibodies?

A

Plasma cells

53
Q

What substance initiates the inflammatory response?

A

Haegman Factor

54
Q

Function of interleukins?

A

stimulate T and B cells
cause fever, myalgia, arthralgia, slow wave sleep
increase activity of b cells, cytotoxic cells, NK
stimulate the production of more t cells

55
Q

Major histocompatibility complex

A

Distinguish self from nonself

56
Q

What is responsible for fever, myalgia, joint pain?

A

Interleukins

57
Q

What is a type of myelocyte?

A

Basophil

58
Q

How long does it take to make antibodies?

A

several days

59
Q

Neoplasms occur when?

A

when mutant cells escape the immune system and multiply

60
Q

What cells stimulate other cells to be more aggressive?

A

T helper cells

61
Q

What immunoglobin is the first to be released upon exposure to an antigen?

A

IgM

62
Q

Full thickness body burns can cause what barriers to be destroyed?

A

Skin & Mucous membranes

63
Q

How many immunoglobins are there?

A

5

64
Q

Complement proteins form a ring around an antigen and do what?

A

alter the antigens membrane
release histamine
induce chemostaxis
increase phagocyte activity

65
Q

Gold salts inhibit what?

A

Phagocytes

66
Q

NSAIDS inhibit what?

A

Prostaglandins

67
Q

Salicylates block what?

A

Prostaglandin activity

68
Q

When can a pt who underwent surgery begin taking aspirin again?

A

1 week (7 day)

69
Q

How is etanercept given?

A

SQ

70
Q

What agent is contraindicated for a pt allegic to tartrazine?

A

Aspirin

71
Q

What is injected into the knee to prevent arthritis?

A

Hyaluronidase

72
Q

How long does it take for penicillamine to take effect?

A

2-3months

73
Q

Acute salycilate toxicity signs?

A

Hyperpnea
Excitement
Tetany

74
Q

When is gold salts contraindicated?

A

DM
HTN
Blood dyscrasias

75
Q

Celebrex is contraindicated in?

A

Sulfa allergies

76
Q

Are there drug to drug interactions for interleukins and interferons?

A

No

77
Q

Which drug causes t cells to be disabled?

A

Muromomab-CD3

78
Q

What is an adverse effect of monoclonal antibodies?

A

Pulmonary edema

79
Q

What is an adverse to immune stimulants?

A

flu like symptoms

80
Q

What is the most common immune suppressant?

A

Cyclosporine

81
Q

What can you mix cylcosporine with?

A

Orange juice, milk, chocolate milk

82
Q

Immune sera

A

bacterial antibodies in serum

83
Q

Vaccines are available for what biological weapons?

A

Anthrax, smallpox, botulism

84
Q

What do you give immune globulin for?

A

Bite from an animal w/rabies

85
Q

Adverse effects of immunizations?

A

irritability
anorexia
chills
redness at site

86
Q

Vaccines are what type of immunity

A

active

87
Q

Example of passive immunity

A

antibodies injected in host

88
Q

Tx for botulism

A

Immune sera

89
Q

With what does serum sickness occur

A

immune sera

90
Q

Caution for vaccines if pt has what?

A

Febrile

Patho Exam 2 Spring 2014 (4 decks)

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