Immune Response Flashcards
Body’s reaction spec. the immune system when a foreign agent enters the body
IMMUNE RESPONSE
Factors Affecting Immune Response:
OACG
OVERALL HEALTH STATUS OF INDIVIDUAL
AGE
CONCENTRATION & ROUTE OF ADMINISTRATION OF ANTIGEN TO THE HOST’S BODY
GENETIC CONTROL OF IMMUNE RESPONSE
Healthy - ___
Weak / Poor - ___
FAST IMMUNE RESPONSE BC IMMUNE CELLS MORE ACTIVE
DEFICIENT / SLOW IMMUNE RESPONSE
Neonatal / Newborns - ___
Geriatrics / Old Patients - ___
IMMUNE SYSTEM STILL DEVELOPING
WEAK IMMUNE SYSTEM –> SLOW IMMUNE RESPONSE
Greater antigen administered = __
FASTER & GREATER IMMUNE RESPONSE
Helps immune cells determine self from non-self
MHC (MAJOR HISTOCOMPATIBILITY COMPLEX)
Occurs in 4 phases after exposure to an antigen
PRIMARY IMMUNE RESPONSE
No antibody is detectable
Immune system process foreign antigens that enter the body
LAG PHASE
Antibody titer increasing logarithmically / spiked
LOG / EXPONENTIAL PHASE
Antibody titer stabilizes
Stationary / stable → equilibrium between antibody production and catabolism
PLATEAU PHASE
Antibody titer decreases / catabolized → catabolism > production
DECLINE PHASE
Elicited by a second by any subsequent exposure to the same antigen
SECONDARY IMMUNE RESPONSE / ANAMNESTIC / MEMORY RESPONSE
Makes it possible for a more rapid Ab response, shorter processing period / Lag phase
MEMORY
Predominant Ab in secondary immune response
IgG
Lag Phase:
Primary - ___
Secondary - ___
LONGER
SHORTER